24566-95-8

Basic information

• Product Name: N-(3-Aminopropyl)-EPSILON-caprolactam
• Synonyms: N-(3-Aminopropyl)-EPSILON-caprolactam;1-(3-Aminopropyl)hexahydro-1H-azepin-2-one;1-(3-Aminopropyl)hexahydro-2H-azepin-2-one;N-(3-Aminopropyl)-ε-caprolactam
• CAS NO: 24566-95-8
• Molecular Formula: C₉H₁₈N₂O
• Molecular Weight: 170.252
• Mol File: 24566-95-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 326 °C at 760 mmHg
• Flash Point: 150.9 °C
• Appearance: /
• Density: 1.004 g/cm³
• Vapor Pressure: 0.000222mmHg at 25°C
• Refractive Index: 1.488
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.83±0.10(Predicted)
• CAS DataBase Reference: N-(3-Aminopropyl)-EPSILON-caprolactam(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-Aminopropyl)-EPSILON-caprolactam(24566-95-8)
• EPA Substance Registry System: N-(3-Aminopropyl)-EPSILON-caprolactam(24566-95-8)

Safety Data

• Hazardous Substances Data: 24566-95-8(Hazardous Substances Data)

Usage

General Description

N-(3-Aminopropyl)-EPSILON-caprolactam, also known as 3-aminopropyl-ε-caprolactam or Aminorigidin, is a chemical compound with the molecular formula C8H16N2O. It is a cyclic amine compound that is used in the production of nylon-6, which is a widely used synthetic polymer. N-(3-Aminopropyl)-EPSILON-caprolactam acts as a monomer in the polymerization process of nylon-6, where it undergoes ring-opening polymerization to form the long chains of the nylon polymer. It is also used in the production of other polymers and as a building block in organic synthesis. The compound has potential applications in industries such as textiles, automotive, and packaging due to its high strength and durability.

InChI:InChI=1/C9H18N2O/c10-6-4-8-11-7-3-1-2-5-9(11)12/h1-8,10H2

Upstream product

• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 
• 123-38-6 propionaldehyde 
• 105-60-2 caprolactam 
• 7336-15-4 hexahydro-1-(2'-cyanoethyl)-2H-azepin-2-one 

Downstream Products

• 1427783-78-5 (Z)-1-(3-(2-oxoazepan-1-yl)propyl)-2-benzoyl-3-(4-chlorophenyl)guanidine 
• 1427783-78-5 (E)-1-(3-(2-oxoazepan-1-yl)propyl)-2-benzoyl-3-(4-chlorophenyl)guanidine 
• 1427783-68-3 (Z)-1-(propyl-2-azepanone)-2-benzoyl-3-(4-bromophenyl)guanidine 
• 1427783-68-3 (E)-1-(propyl-2-azepanone)-2-benzoyl-3-(4-bromophenyl)guanidine 
• 1270171-45-3 4-[N-(3′-aminopropyl)-2-azepanone]-3-nitrobenzenesulfonic acid 
• 1270171-48-6 4-[N-(3'-aminopropyl)-2-azepanone]-3-nitrobenzenesulfonic acid 
• 1270171-53-3 N,N-dimethylaminopropyl-4-[N-(3'-aminopropyl)-2-azepanone]-3-nitrobenzoate 
• 1270171-56-6 N,N-diethylaminopropyl-4-[N-(3'-aminopropyl)-2-azepanone]-3-nitrobenzoate 
• 1197209-33-8 C₃₂H₃₆N₄O₄ 
• 1197209-34-9 C₄₅H₃₈N₄O₅ 
• 1082008-29-4 4-{2-[(3-chlorophenyl)amino]pyrimidin-4-yl}-N-[3-(2-oxoazepan-1-yl)propyl]pyridine-2-carboxamide 
• 3437-33-0 N-(3-aminopropyl)hexamethyleneimine 

Relevant articles and documents

A facile synthesis of the intermediates of the bicyclic organic bases: DBU and TBD

Intermediates of DBU and TBD, N-(3-aminoproply) - ε -caprolactam and bis- (3-aminopropyl)-amine were prepared by the hydrogenolysis of N-(2-cyanoethyl) - ε - caprolactam and di- (β-cyanoethyl)-amine respectively over Raney-Ni in the presence of NaBH4 under atmospheric pressure with mild condition and good yield.

HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF

Described herein are compounds that are inhibitors of autophagy and their use in the treatment of disorders such as cancers. (I)

N-Heterocyclic Olefin Catalysis for the Ring Opening of Cyclic Amidine Compounds: A Pathway to the Synthesis of ?-Caprolactam- and γ-Lactam-Derived Amines

For the first time, 1,2-dimethyl-3-ethylimidazolium iodide (1a) catalyzes the ring opening of the bicyclic amidine system of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) or DBN (1,5-diazabicyclo[4.3.0]non-5-ene) on reaction with aldehydes. The mechanism here