24567-08-6

Basic information

• Product Name: 3,4-diphenyl-2H-pyrazole
• Synonyms: 3,4-diphenyl-2H-pyrazole;3,4-Diphenyl-1H-pyrazole
• CAS NO: 24567-08-6
• Molecular Formula: C₁₅H₁₂N₂
• Molecular Weight: 220.27
• Mol File: 24567-08-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 396.9 °C at 760 mmHg
• Flash Point: 180.8 °C
• Appearance: /
• Density: 1.149 g/cm³
• Vapor Pressure: 3.79E-06mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 3,4-diphenyl-2H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-diphenyl-2H-pyrazole(24567-08-6)
• EPA Substance Registry System: 3,4-diphenyl-2H-pyrazole(24567-08-6)

Safety Data

• Hazardous Substances Data: 24567-08-6(Hazardous Substances Data)

Usage

General Description

3,4-diphenyl-2H-pyrazole, also known as diphenylpyrazole, is a chemical compound with the molecular formula C16H14N2. It is a heterocyclic organic compound containing a pyrazole ring with two phenyl groups attached at positions 3 and 4. 3,4-diphenyl-2H-pyrazole has several industrial and pharmaceutical applications, including as a building block in the synthesis of various pharmaceutical drugs and agrochemicals. It is also used as a ligand in coordination chemistry and as a component in organic light-emitting diodes (OLEDs) and other optoelectronic devices. Additionally, 3,4-diphenyl-2H-pyrazole has been studied for its potential biological activities, including antimicrobial and anti-inflammatory properties.

InChI:InChI=1/C15H12N2/c1-3-7-12(8-4-1)14-11-16-17-15(14)13-9-5-2-6-10-13/h1-11H,(H,16,17)

Upstream product

• 4545-20-4 benzophenone tosylhydrazone 
• 75-20-7 calcium carbide 
• 447-31-4 Desyl chloride 
• 908093-98-1 diazodiphenylmethane 
• 50779-86-7 dimethyl 3,4-diphenyl-4H-pyrazole-4,5-dicarboxylate 
• 31419-01-9 dimethyl 3,3-diphenyl-3H-pyrazole-4,5-dicarboxylate 
• 412306-23-1 5-methyl-4-nitro-3,3-diphenyl-4,5-dihydro-3H-pyrazole 
• 93020-59-8 2-methylsulfanyl-5,6-diphenyl-6H-[1,3,4]thiadiazine 
• 51463-88-8 3-Methyl-4,5-diphenylpyrazole 
• 501-65-5 diphenyl acetylene 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 32258-63-2 4,5-diphenyl-1⁽²⁾H-pyrazole-3-carboxylic acid 
• 97953-53-2 3-methylsulfanyl-4,5-diphenyl-1⁽²⁾H-pyrazole 
• 5669-11-4 3-oxo-2,3-diphenylpropanal 

Downstream Products

• 134701-93-2 8-(3,4-Diphenyl-pyrazol-1-yl)-octanoic acid methyl ester 
• 134701-94-3 8-(4,5-Diphenyl-pyrazol-1-yl)-octanoic acid methyl ester 
• 134701-71-6 methyl 3,4-diphenyl-1H-pyrazole-1-nonanoate 
• 134701-72-7 methyl 4,5-diphenyl-1H-pyrazole-1-nonanoate 
• 131362-17-9 methyl <3-<2-(4,5-diphenyl-1H-pyrazol-1-yl)ethyl>phenoxy>acetate 
• 131362-16-8 methyl <3-<2-(3,4-diphenyl-1H-pyrazol-1-yl)ethyl>phenoxy>acetate 
• 94483-90-6 N-methyl-3,4-diphenyl-1H-pyrazole-1-propanamine 
• 67455-52-1 1-(2-cyanoethyl)-3,4-diphenylpyrazole 
• 94483-87-1 3,4-diphenyl-1H-pyrazole-1-propanamine 
• 94483-95-1 N,N-diethyl-3,4-diphenyl-1H-pyrazole-1-propanamine 
• 94483-96-2 N,N-diethyl-4,5-diphenyl-1H-pyrazole-1-propanamine 
• 39672-48-5 4,5-Diphenyl-1,2,3-triazin 
• 99939-03-4 3,4-Diphenyl-1H-pyrazol-1-amin 
• 134701-73-8 3,4-diphenyl-1H-pyrazole-1-nonanoic acid 

Relevant articles and documents

Calcium carbide as the acetylide source: Transition-metal-free synthesis of substituted pyrazoles via [1,5]-sigmatropic rearrangements

Under transition-metal-free conditions, calcium carbide was used as the acetylide source to react with a wide range of N-tosylhydrazones derived from aldehydes or ketones, affording various substituted pyrazoles in good yields with high regioselectivities. The transformations go through [3 + 2] cycloadditions followed by [1,5]-sigmatropic rearrangements, which are supported by deuterium-labeling experiments.

Microwave-assisted synthesis of pyrazoles by 1,3-dipolar cycloaddition of diazo compounds to acetylene derivatives

Microwave-assisted preparation of a wide range of 5-ethoxycarbonylpyrazoles and 3-pyrazoles by 1,3-dipolar cycloaddition of diazo compound to acetylenes is described. All reactions were carried out using high throughput sequential technique.{A figure is p