245759-65-3

Basic information

• Product Name: (R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol
• Synonyms: (R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol
• CAS NO: 245759-65-3
• Molecular Weight: 526.632
• Mol File: 245759-65-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol(245759-65-3)
• EPA Substance Registry System: (R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol(245759-65-3)

Safety Data

• Hazardous Substances Data: 245759-65-3(Hazardous Substances Data)

Usage

Description

(R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol is a complex organic chemical compound characterized by its multiple functional groups, including a nitro group, a benzene ring, an alcohol group, and several aromatic rings. (R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol also features an amino group and a methoxy group, contributing to its structural complexity. The combination of these functional groups suggests potential pharmacological or biological properties, although further testing and analysis are required to confirm its specific uses and effects.

Uses

Used in Pharmaceutical Industry:
(R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol is used as a potential pharmaceutical compound for its possible pharmacological or biological properties. The presence of various functional groups in its structure may allow it to interact with biological targets, making it a candidate for drug development.
Used in Chemical Research:
In the field of chemical research, (R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol can be utilized as a starting material or a building block for the synthesis of other complex molecules. Its unique structure may facilitate the development of new chemical entities with specific applications in various industries.
Used in Material Science:
(R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol's structural complexity and the presence of multiple functional groups may also make it a candidate for material science applications. It could potentially be used in the development of new materials with specific properties, such as improved conductivity, stability, or reactivity.
Please note that the specific applications mentioned above are hypothetical and based on the compound's structural features. Actual uses would depend on the results of further research, testing, and analysis.

Upstream product

• 1198769-18-4 (R)-4-benzyloxy-3-nitro-α-(N-benzyl-N-(1-methyl-2-p-methoxyphenylethyl)amino)acetophenone 
• 67346-60-5 (R)-(-)-1-(4'-methoxyphenyl)-2-benzylaminopropane 
• 1049695-95-5 benzyl-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine; hydrochloride 
• 245759-64-2 (R)-N-benzyl-N-(1-methyl-2-p-methoxyphenylethyl)amine L-mandelate 
• 188690-82-6 (R)-2-bromo-1-(4-benzyloxy-3-nitrophenyl)ethanol 
• 122-84-9 4-methoxybenzyl methyl ketone 
• 188730-94-1 (R)-1-(4-benzyloxy-3-nitrophenyl)oxirane 
• 1096141-37-5 C₁₇H₁₉NO 
• 43229-65-8 [2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amine 
• 100-46-9 benzylamine 
• 43229-01-2 4-benzyloxy-3-nitrophenacyl bromide 

Downstream Products

• 73573-87-2 (R,R)-formoterol 
• 188690-83-7 N-[5-[(1R)-Hydroxy-2-[[(1R)-methyl-2-(4-methoxyphenyl)ethyl](phenylmethyl)amino]ethyl]-2-(phenylmethoxy)phenyl]-formamide 
• 289657-26-7 (R,R)-3-amino-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenyl methyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol 

Relevant articles and documents

PROCESSES FOR PREPARING SUBSTANTIALLY PURE ARFORMOTEROL AND ITS INTERMEDIATES

Provided herein are improved, convenient and industrially advantageous processes for the preparation of N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide (Arformoterol) or a pharmaceutically acceptable salt thereof, in high yield and purity. Provided further herein is an improved and industrially advantageous process for the preparation of a substantially enantiomerically pure arformoterol intermediate, (R)-4-methoxy-α-methyl-N-(phenylmethyl)benzeneethanamine.

Enantio- and diastereoselective synthesis of all four stereoisomers of formoterol

Enantioselective syntheses of all four stereoisomers of formoterol are accomplished using asymmetric catalytic borane reductions with chiral oxazaborolidines as reducing agents.