246035-38-1

Basic information

• Product Name: (S)-2-Benzothiazolyl (Z)-2-(2-aminothiazole-4-yl)-2-methoxycarbonylmethoxyiminothioacetate
• Synonyms: (S)-2-BENZOTHIAZOLYL (Z)-2-(2-AMINOTHIAZOLE-4-YL)-2-METHOXYCARBONYLMETHOXYIMINOTHIOACETATE;(S)-2-Benzothiazoly;2-MERCAPTOBENZOTRIAZOYL-(Z)-2-(2-AMINOTHIAZOLE-4-YL)-2-(METHYOXYCARBONYL METHOXYIMINO)ACETATE (MICA ESTER);(Z)-Methyl 2-(((1-(2-aMinothiazol-4-yl)-2-(benzo[d]thiazol-2-ylthio)-2-oxoethylidene)aMino)oxy)acetate;Acetic acid,2-[[(Z)-[1-(2-aMino-4-thiazolyl)-2-(2-benzothiazolylthio)-2-oxoethylidene]aMino]oxy]-,Methyl ester;(S)-2-Benzothiazolyl (Z)-2-(Amino-Thiazole-4-yl)-2-Methoxy-carbonyl-methoxyiminothio-acetate;S-2-BENZOTHIAZOL-2-(2-AMINO-THIAZOL-4YL)-2- (METHOXYCARBONYL METHYLOXYIMINOTHIOACETATE;Mica Ester (S-2-Benzothiazolyl (Z)-2-(2-Aminothiazole-4-Yl)-2-Methoxy-Carbonylmethio Acetate)
• CAS NO: 246035-38-1
• Molecular Formula: C15H12N4O4S3
• Molecular Weight: 408.48
• Mol File: 246035-38-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 610.999 °C at 760 mmHg
• Flash Point: 323.321 °C
• Appearance: /
• Density: 1.636 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.761
• Storage Temp.: 2-8°C
• PKA: 0?+-.0.10(Predicted)
• CAS DataBase Reference: (S)-2-Benzothiazolyl (Z)-2-(2-aminothiazole-4-yl)-2-methoxycarbonylmethoxyiminothioacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Benzothiazolyl (Z)-2-(2-aminothiazole-4-yl)-2-methoxycarbonylmethoxyiminothioacetate(246035-38-1)
• EPA Substance Registry System: (S)-2-Benzothiazolyl (Z)-2-(2-aminothiazole-4-yl)-2-methoxycarbonylmethoxyiminothioacetate(246035-38-1)

Safety Data

• Hazardous Substances Data: 246035-38-1(Hazardous Substances Data)

Usage

General Description

(S)-2-Benzothiazolyl (Z)-2-(2-aminothiazole-4-yl)-2-methoxycarbonylmethoxyiminothioacetate is a complex chemical compound with a long and intricate name. It is a derivative of thiazole, a heterocyclic compound containing both sulfur and nitrogen atoms. (S)-2-Benzothiazolyl (Z)-2-(2-aminothiazole-4-yl)-2-methoxycarbonylmethoxyiminothioacetate is a methoxycarbonylmethoxyiminothioester, meaning it contains both an ester and an iminothio functional group. It also contains a benzothiazolyl and an aminothiazole-4-yl group. With its various functional groups and complex structure, this compound may have potential applications in pharmaceuticals, biotechnology, or materials science.

InChI:InChI=1/C15H12N4O4S3/c1-22-11(20)6-23-19-12(9-7-24-14(16)17-9)13(21)26-15-18-8-4-2-3-5-10(8)25-15/h2-5,7H,6H2,1H3,(H2,16,17)/b19-12-

Upstream product

• 80544-17-8 2-(2-aminothiazol-4-yl)-2-[(Z)-methoxycarbonylmethoxyimino]acetic acid 
• 120-78-5 di(benzothiazol-2-yl)disulfide 

Relevant articles and documents

AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME

There is provided an improved process for preparing cefixime. Thus, for example, 7-amino-3-vinyl-3-cephem-4-carboxylic acid is reacted with 2-mercapto-1,3-benzothiazolyl-(Z)-2-(2-aminothiazol-4-yl)-2-(methoxycarbonyl)-methoxyimino acetate in tetrahydrofuran and water at 4°C in the presence of triethylamine. The reaction mass is extracted with ethyl acetate. 7-[2-(2-Amino-4-thiazolyl)-2-(methoxycarbonylmethoxyimino)acetamido]-3-vinyl-3-cephem-4-carboxylic acid triethylamine salt present in the aqueous layer is hydrolyzed with sodium hydroxide in less than 30 minutes and aqueous hydrochloric acid is added immediately to adjust the pH to 4.8 to 5.2. Then, aqueous hydrochloric acid is added at 35°C to adjust the pH 2.5 and cooled to crystallize cefixime trihydrate in high purity.