2465-11-4

Basic information

• Product Name: (22E)-5α-Ergosta-7,22-dien-3β-ol
• Synonyms: α-Dihydroergosterol;(22E)-Ergosta-7,22-dien-3β-ol;(22E,24R)-Ergosta-7,22-dien-3β-ol;(24S)-24-Methyl-5α-cholesta-7,22-dien-3β-ol;(3β,5α,22E)-Ergosta-7,22-dien-3-ol;24-Methyl-5α-cholesta-7,22-dien-3β-ol;5-Dihydroergosterin;Ergosta-7,22-dienol
• CAS NO: 2465-11-4
• Molecular Formula: C₂₈H₄₆O
• Molecular Weight: 398.66424
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
• Mol File: 2465-11-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 487.5 °C at 760 mmHg
• Flash Point: 213 °C
• Appearance: /
• Density: 0.99 g/cm³
• Vapor Pressure: 1.5E-11mmHg at 25°C
• Refractive Index: 1.532
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
• CAS DataBase Reference: (22E)-5α-Ergosta-7,22-dien-3β-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (22E)-5α-Ergosta-7,22-dien-3β-ol(2465-11-4)
• EPA Substance Registry System: (22E)-5α-Ergosta-7,22-dien-3β-ol(2465-11-4)

Safety Data

• Hazardous Substances Data: 2465-11-4(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 2465-11-4 differently. You can refer to the following data:
1. One of the six sterols isolated from the fruiting bodies of Boletus pulverulentus Opat. (Boletaceae) and identified as (22E)-Ergosta-5,7,9(11),22-tetraen-3β-ol, Ergosterol, Ergosta-5,7-dien-3β-ol, (22 E)-Ergosta-5,8,22-trien-3β-ol, (22E)-Ergosta-7,22-dien-3β-ol (Stellasterol), and Ergost-7-en-3β-ol.
2. One of the six sterols isolated from the fruiting bodies of Boletus pulverulentus Opat. (Boletaceae) and identified as (22E)-Ergosta-5,7,9(11),22-tetraen-3β-ol, Ergosterol, Ergosta-5,7-dien-3β-ol, (22E)-Ergosta-5,8,22-trien-3β-ol, (22E)-Ergosta-7,22-dien-3β-ol (Stellasterol), and Ergost-7-en-3β-ol.

Definition

ChEBI: A 3beta-sterol consisting of an ergostane skeleton with double bonds at 7- and 22-positions.

InChI:InChI=1/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-8,10,18-22,24-26,29H,9,11-17H2,1-6H3/b8-7+/t19-,20+,21-,22-,24+,25-,26-,27-,28+/m0/s1

Upstream product

• 5035-30-3 (3β,22E)-ergosta-5,7,22-trien-3-ol benzoate 
• 64-17-5 ethanol 
• 516-85-8 9⁽¹¹⁾-dehydroergosterol 
• 71-23-8 propan-1-ol 
• 28421-56-9 3β-acetoxy-5α,8α-(4-phenyl-1,2,4-triazolidine-3,5-dione-1,2-diyl)ergosta-6,22-diene 
• 10123-90-7 3β-hydroxy-3',5'-dioxo-4'-phenyl-5,8<1',2'>-1',2',4'-triazolidino-5α,8α-ergosta-6,22-diene 
• 95307-26-9 3β-tert-Butyldimethylsilyloxy-ergosta-5,7,22-triene 
• 95307-27-0 O-methoxymethyl-ergosterol 
• 142186-92-3 ergosta-7,22-dien-3β-yl palmitate 
• 57-87-4 Ergosterol 

Downstream Products

• 632-32-6 (3β,5α)-ergost-8(14)-en-3-ol 
• 516-78-9 (3β,5α)-ergost-7-en-3-ol 
• 1449-60-1 5-dihydroergosteryl acetate 
• 55401-50-8 (3S,5S,8R,9S,10S,13R,17R)-17-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate 
• 1542168-60-4 N-[(3α)-ergosta-7,22E-dien-3-yl]-N-methyl-2-nitrobenzenesulfonamide 
• 23839-47-6 ignosterol 
• 1449-60-1 5α-ergostadien-(7.22t)-yl-(3α)-acetate 
• 2680-10-6 5α-ergostatrien-(7.9(11).22t)-yl-(3α)-acetate 
• 116282-74-7 3.5-dinitro-benzoic acid-(5α.10α-ergostanyl-(3α)-ester) 
• 1449-60-1 5α.10α-ergostadien-(7.22t)-yl-(3α)-acetate 
• 474-59-9 24β_F-methyl-5α.10α-cholestanol-(3α) 
• 1449-60-1 5β-lumistadien-(7.22t)-yl-(3α)-acetate 
• 474-59-9 (10S)-3c-Hydroxy-10r.13c-dimethyl-17c-((1R:4S)-1.4.5-trimethyl-hexyl)-(5ξH.8ξH.9cH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthren 

Relevant articles and documents

A LANOSTANOID OF FORMOSAN GANODERMA LUCIDUM

A new steryl ester, ergosta-7,22-dien-3β-yl palmitate, a novel lanostanoid, named ganoderic aldehyde A (3β-hydroxy-26-oxo-5α-lanosta-8,24-dien-11-one, ergosta-7,22-dien-3β-ol, ergosta-7,22-dien-3-one, and ergosterol peroxide, were isolated from the fruit bodies of Formosan Ganoderma lucidum and characterized by chemical degradation, synthesis, and spectral data.

Selective Reduction of the 7(8)-Double Bond in Ergosterol

Reduction of ergosterol alkoxide derivatives with lithium metal gives better yields of the 7(8)-reduced product brassicasterol than previous procedures; the mixed products of the reduction are easily converted into ergosta-2,22-dien-6-one, a convenient in

A Simple Method for the Reduction of the 7,8-Double Bond of Steroidal 5,7-Dienes

1,4-Cycloadducts of various steroidal 5,7-dienes and 4-phenyl-1,2,4-triazoline-3,5-dione gave a separable mixture (3 : 2) of the corresponding Δ5- and Δ7-sterols in good yield when treated with lithium dissolved in refluxing ethylamine.