24707-99-1

Basic information

• Product Name: Trimethylsilyl 2-O,3-O,4-O,6-O-tetrakis(trimethylsilyl)-α-D-mannopyranoside
• Synonyms: Trimethylsilyl 2-O,3-O,4-O,6-O-tetrakis(trimethylsilyl)-α-D-mannopyranoside
• CAS NO: 24707-99-1
• Molecular Formula: C₂₁H₅₂O₆Si₅
• Molecular Weight: 541.06148
• Mol File: 24707-99-1.mol
• Article Data: 67

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Trimethylsilyl 2-O,3-O,4-O,6-O-tetrakis(trimethylsilyl)-α-D-mannopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: Trimethylsilyl 2-O,3-O,4-O,6-O-tetrakis(trimethylsilyl)-α-D-mannopyranoside(24707-99-1)
• EPA Substance Registry System: Trimethylsilyl 2-O,3-O,4-O,6-O-tetrakis(trimethylsilyl)-α-D-mannopyranoside(24707-99-1)

Safety Data

• Hazardous Substances Data: 24707-99-1(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 59-23-4 D-Galactose 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 10257-28-0 D-Galactose 
• 2280-44-6 D-Glucose 
• 73-34-7 D-Fucose 
• 18156-74-6 1-(Trimethylsilyl)imidazole 
• 50-99-7 D-glucose 
• 1015696-25-9 (25R)-26-O-β-D-glucopyranosyl-22α-methoxy-5α-furostan-3β,26-diol 3-O-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->3)]-β-D-glucopyranosyl-(1->4)-β-D-galactopyranoside 
• 1374792-02-5 (25R)-26-O-β-D-glucopyranosyl-22α-methoxy-5α-furostan-3β,26-diol 3-O-β-D-xylopyranosyl-(1->3)-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->3)]-β-D-glucopyranosyl-(1->4)-β-D-galactopyranoside 
• 2754-27-0 trimethylsilyl acetate 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 

Downstream Products

• 352432-46-3 2,3,4,6-tetrakis-O-trimethylsilyl-α-D-glucopyranosyl iodide 
• 1541195-51-0 (2S,3S,4R)-2-azido-3,4-O-dibenzyl-1-O-α-D-galactopyranosyloctadec-6-ene-1,3,4-triol 
• 1541195-95-2 C₅₀H₈₉N₃O₈Si₄ 
• 1613320-91-4 (2S,3S,4R)-3,4-O-dibenzyl-1-O-α-D-galactopyranosyl-2-hexacosanoylaminooctadec-6-ene-1,3,4-triol 
• 4050-45-7 trans-2-hexene 
• 110-54-3 hexane 
• 96-14-0 3-methylpentane 
• 107-83-5 2-Methylpentane 
• 942043-17-6 4-methylphenyl 2,3,4,6-tetrakis-O-trimethylsilyl-1-thio-β-D-glucopyranoside 

Relevant articles and documents

Development of a Novel Method for Trimethylsilylation of Saccharides?

The trimethylsilyl (TMS) group is widely used in carbo?hydrate synthesis, although this protecting group is unstable and its post-synthetic purification challenging. The successful trimethylsilyl?ation of carbohydrates mediated by recyclable and efficient

A practical and scalable synthesis of KRN7000 using glycosyl iodide as the glycosyl donor

KRN7000 is particularly useful because it is a powerful and specific CD1d agonist and has prompted intense interest in the context of immunology in the past 25 years. Its limited commercial availability and high price has led to the publication of many different syntheses. However, almost all of them focused on the methodology development rather than a scalable synthesis. Herein, we have described a practical and scalable procedure for the synthesis of KRN7000 basing on the glycosyl iodide method. This procedure involves total of eight steps to obtain the highly pure product KNR7000 on gram scale from the commercially available starting materials (d-galactose and the phytosphingosine) with only three column chromatographic purifications.

A palladium-catalyzed approach to allenic aromatic ethers and first total synthesis of terricollene A

A palladium-catalyzed C-O bond formation reaction between phenols and allenylic carbonates to give 2,3-allenic aromatic ethers with decent to excellent yields under mild reaction conditions has been described. A variety of synthetically useful functional