24743-11-1

Basic information

• Product Name: 4-(3-methoxyphenyl)butanoic acid
• Synonyms: 3-Methoxybenzenebutanoic acid;4-(3-Methoxyphenyl)butanoic acid;Benzenebutanoic acid, 3-methoxy-;4-(3-Methoxy-phenyl)-butyric acid
• CAS NO: 24743-11-1
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.2271
• Mol File: 24743-11-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 334.3°Cat760mmHg
• Flash Point: 129.1°C
• Appearance: /
• Density: 1.116g/cm³
• Vapor Pressure: 5.09E-05mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: 4-(3-methoxyphenyl)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-methoxyphenyl)butanoic acid(24743-11-1)
• EPA Substance Registry System: 4-(3-methoxyphenyl)butanoic acid(24743-11-1)

Safety Data

• Hazardous Substances Data: 24743-11-1(Hazardous Substances Data)

Usage

General Description

4-(3-methoxyphenyl)butanoic acid, also known as GABA, is a chemical compound that has been studied for its potential medicinal properties. It is a derivative of butyric acid and contains a 3-methoxyphenyl group. GABA has been investigated for its potential as a GABA receptor agonist, which could have implications for its use in the treatment of neurological disorders. Additionally, GABA has been studied for its potential as an anti-inflammatory and anti-cancer agent.

InChI:InChI=1/C11H14O3/c1-14-10-6-2-4-9(8-10)5-3-7-11(12)13/h2,4,6,8H,3,5,7H2,1H3,(H,12,13)

Upstream product

• 111171-90-5 (3-methoxy-phenethyl)-malonic acid diethyl ester 
• 625-38-7 but-3-enoic acid 
• 10365-98-7 3-methoxyphenylboronic acid 
• 2398-37-0 3-methoxyphenyl bromide 
• 24743-14-4 1-allyl-3-methoxybenzene 
• 100-66-3 methoxybenzene 
• 1798-09-0 m-methoxyphenylacetic acid 
• 18904-42-2 4-(m-Methoxy-phenyl)-Δ³-butensaeure-ethylester 
• 194932-65-5 C₁₃H₁₆O₃ 
• 65292-99-1 2-(3-methoxyphenyl)acetaldehyde 
• 51114-94-4 (2-carboxyethyl)triphenylphosphonium bromide 
• 603-35-0 triphenylphosphine 
• 137744-81-1 (E)-4-(m-methoxyphenyl)but-3-enoic acid 
• 591-31-1 3-methoxy-benzaldehyde 

Downstream Products

• 77259-95-1 γ-(2-bromo-5-methoxyphenyl)butyric acid 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 24743-09-7 8-(3-methoxy-phenyl)-5-oxo-octanoic acid 
• 77259-96-2 5-Brom-8-methoxy-1,2,3,4-tetrahydro-1-naphthalinon 
• 6836-19-7 7-Methoxy-1-tetralone 
• 20175-97-7 7-methoxy-3,4-dihydronaphthalen-1(2H)-one oxime 
• 1610999-42-2 3-[4-(4-phenylpiperazin-1-yl)butyl]phenol 
• 1610999-41-1 1-[4-(3-methoxyphenyl)butyl]-4-phenylpiperazine 
• 1610999-39-7 4-(3-methoxyphenyl)-1-(4-phenylpiperazin-1-yl)butan-1-one 
• 6321-53-5 2-[2-(3-methoxyphenyl)ethyl]cyclohexane-1,3-dione 
• 22921-68-2 2-bromo-5-methoxy-benzoic acid 
• 77260-16-3 N-[8-Bromo-5-methoxy-4a-methyl-4,4a,9,10-tetrahydro-3H-phenanthren-(2E)-ylidene]-N'-(2,4-dinitro-phenyl)-hydrazine 
• 77260-18-5 N-(2,4-Dinitro-phenyl)-N'-[5-methoxy-4a-methyl-4,4a,9,10-tetrahydro-3H-phenanthren-(2E)-ylidene]-hydrazine 
• 77260-11-8 N-[5-Bromo-8-methoxy-1-methyl-3,4-dihydro-1H-naphthalen-(2E)-ylidene]-N'-(2,4-dinitro-phenyl)-hydrazine 

Relevant articles and documents

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A heavy-metal-free desulfonylative Giese-type reaction of benzothiazole sulfones under visible-light conditions

A visible-light-induced desulfonylative Giese-type reaction has been developed. Essential to the success is the employment of Hantzsch ester to activate benzothiazole sulfones without any heavy-metal additives. Not only benzylic benzothiazole sulfones but also alkyl ones were viable substrates and reacted with electron-deficient alkenes and a propiol amide.

Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals

In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.