2483-65-0

Basic information

• Product Name: 3-AMINO-PYRROLIDIN-2-ONE
• Synonyms: 3-Amino-2-pyrrolidinone;3-aminopyrrolidin-2-one(SALTDATA: FREE);2-Pyrrolidinone, 3-aMino-;D,L-3-aMino-2-pyrrolidinone;3-Amino-2-oxopyrrolidine;rac 3-Amino-pyrrolidin-2-one, 98%
• CAS NO: 2483-65-0
• Molecular Formula: C₄H₈N₂O
• Molecular Weight: 100.12
• Mol File: 2483-65-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 106-108℃
• Boiling Point: 305.589 °C at 760 mmHg
• Flash Point: 138.616 °C
• Appearance: /
• Density: 1.127 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.486
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 15.92±0.40(Predicted)
• CAS DataBase Reference: 3-AMINO-PYRROLIDIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-PYRROLIDIN-2-ONE(2483-65-0)
• EPA Substance Registry System: 3-AMINO-PYRROLIDIN-2-ONE(2483-65-0)

Safety Data

• Statements: 22
• Hazardous Substances Data: 2483-65-0(Hazardous Substances Data)

Usage

General Description

3-Amino-pyrrolidin-2-one, also known as 3-aminopyrrolidin-2-one or AP-2, is a chemical compound with the molecular formula C4H8N2O. It is a heterocyclic organic compound that contains a pyrrolidin-2-one ring with an amino group attached at the third position. 3-Amino-pyrrolidin-2-one has potential applications in the pharmaceutical industry, particularly in the development of drugs for the treatment of various central nervous system disorders. It also has uses in the synthesis of other organic compounds. Additionally, it may have potential as a building block for the creation of new materials in the fields of chemistry and material science. Its properties and applications make 3-Amino-pyrrolidin-2-one an important compound with potential for various industries and scientific research.

InChI:InChI=1/C4H8N2O/c5-3-1-2-6-4(3)7/h3H,1-2,5H2,(H,6,7)

Upstream product

• 1003-51-6 3-amino-1-hydroxypyrrolidin-2-one 
• 305-62-4 2,4-diaminobutanoic acid 
• 6970-28-1 DL-2,4-diaminobutyric acid dihydrochloride 
• 49846-91-5 methyl 4,5-dihydro-1H-pyrazole-3-carboxylate 
• 37529-96-7 methyl ester of 2,4-diaminobutyric acid 

Downstream Products

• 99780-97-9 (2-oxo-pyrrolidin-3-(S)-yl)-carbamic acid tert-butyl ester 
• 1208005-10-0 3-[{1[bis(4-Chlorophenyl)methyl]azetidin-3-yl}(methyl-sulphonyl)amino]-5-fluoro-N-(2-oxopyrrolidin-3-yl)benzamide 
• 305-62-4 2,4-diaminobutanoic acid 

Relevant articles and documents

PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS

The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.

Catalytic hydrogenation of methyl esters of some 1H-pyrazoline-3-carboxylic acids

Hydrogenation over Raney nickel of the methyl ester of 1H-pyrazoline-3- carboxylic acid and also of its 4-phenyl and 5-methoxycarbonyl-substituted analogs, leads respectively to 3-aminopyrrolidin-2-one, its 4-phenyl- and 5-methoxycarbonyl derivatives, pre

N-type calcium channel blockers

The invention relates to novel 3-amino pyrrolidine derivatives, as well as methods for modulating calcium channel activity and for treating conditions associated with calcium channel function. In particular, the compounds generally contain at least one be