249503-56-8

Basic information

• Product Name: 4-acetyl-3-methoxybenzoic acid
• CAS NO: 249503-56-8
• Molecular Weight: 194.187
• Mol File: 249503-56-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-acetyl-3-methoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetyl-3-methoxybenzoic acid(249503-56-8)
• EPA Substance Registry System: 4-acetyl-3-methoxybenzoic acid(249503-56-8)

Safety Data

• Hazardous Substances Data: 249503-56-8(Hazardous Substances Data)

Upstream product

• 328-42-7 Oxalacetic acid 
• 116934-78-2 5-acetyl-4-methoxy-2-pyrone 

Relevant articles and documents

Substrate Diversity of Macrophomate Synthase Catalyzing an Unusual Multistep Transformation from 2-Pyrones to Benzoates

Macrophomale synthase, which we have recently purified, catalyzes an unusual multistep transformation from 5-acetyl-4-methoxy-6-methyl-2-pyrone to 4-acetyl-3-methoxy-5-methyl-benzoic acid (macrophomic acid). To investigate the substrate diversity of the enzyme, 40 analogs of 2-pyrone were prepared and their relative efficiency was examined in the enzymatic conversions. The experimental results reveal the structural requirements of the substrates and the rough size of the enzyme active site, and eliminate the ambiguity caused by contamination by other enzymes in the whole-cell experiments.