250220-36-1

Basic information

• Product Name: (3-PHENYL-1H-INDEN-1-YLIDENE)BIS(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(IV) DICHLORIDE TETRAHYDROFURAN ADDUCT
• Synonyms: NEOLYST(TM) M1;Bis(tricyclohexylphosphine)-3-phenyl-1H-inden-1-ylideneruthenium(II)dichlorideNeolystM1;(3-phenyl-1h-inden-1-ylidene)bis(tricyclohexylphosphine)ruthenium(iv) dichloride;Bis(tricyclohexylphosphine)-3-phenyl-1H-inden-1-ylideneruthenium(II)dichloride;BIS(TRICYCLOHEXYLPHOSHINE)-3-PHENYL-1H-INDEN-1-YLIDENERUTHENIUM(IV) DICHLORIDE, NEOLYST(TM) M1;DICHLORO(3-PHENYL-1H-INDEN-1-YLIDENE)BIS(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(IV);DICHLORO-(3-PHENYL-1H-INDEN-1-YLIDENE)BIS(TRICYCLOHEXYLPHOSPHINE)-RUTHENIUM(II);Bis(triicyclohexylphosphine)[(phenylthio)methylene]ruthenium(II)dichloride
• CAS NO: 250220-36-1
• Molecular Formula: C₅₁H₇₆Cl₂P₂Ru
• Molecular Weight: 923.07
• EINECS: 480-140-0
• Product Categories: Metal Compounds;Catalysts for Organic Synthesis;Classes of Metal Compounds;Homogeneous Catalysts;Metal Complexes;Ru (Ruthenium) Compounds;Synthetic Organic Chemistry;Transition Metal Compounds;metal phosphine complex;Ru
• Mol File: 250220-36-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 120-141°C
• Boiling Point: 383.4oC at 760 mmHg
• Flash Point: 195.6oC
• Appearance: brown/Powder
• Vapor Pressure: 9.7E-06mmHg at 25°C
• Storage Temp.: 2-8°C
• Water Solubility: Insoluble in water
• CAS DataBase Reference: (3-PHENYL-1H-INDEN-1-YLIDENE)BIS(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(IV) DICHLORIDE TETRAHYDROFURAN ADDUCT(CAS DataBase Reference)
• NIST Chemistry Reference: (3-PHENYL-1H-INDEN-1-YLIDENE)BIS(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(IV) DICHLORIDE TETRAHYDROFURAN ADDUCT(250220-36-1)
• EPA Substance Registry System: (3-PHENYL-1H-INDEN-1-YLIDENE)BIS(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(IV) DICHLORIDE TETRAHYDROFURAN ADDUCT(250220-36-1)

Safety Data

• Hazard Codes: F,Xn
• Statements: 36/37/38-40-11
• Safety Statements: 26-36/37/39-36/37-24/25
• RIDADR: UN1325 - class 4.1 - PG 2 - Flammable solids, organic, n.o.s., H
• WGK Germany: 3
• Hazardous Substances Data: 250220-36-1(Hazardous Substances Data)

Usage

Reaction

Highly active, air-stable catalyst used for the ring closing metathesis of dienes. Used in cross-metathesis.

Chemical Properties

Red powder

Uses

Different sources of media describe the Uses of 250220-36-1 differently. You can refer to the following data:
1. (3-Phenyl-1H-inden-1-ylidene)bis(tricyclohexylphosphine)rutheniuM(IV) Dichloride is used in cross-metathesis reactions as a catalyst involving the involving the petrochemical and biodiesel industries.
2. Metathesis Catalyst

InChI:InChI=1/2C18H33P.C15H10.2ClH.Ru/c2*1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;1-2-6-12(7-3-1)15-11-10-13-8-4-5-9-14(13)15;;;/h2*16-18H,1-15H2;1-9,11H;2*1H;/q;;;;;+2/p-2/r2C18H33P.C15H10Cl2Ru/c2*1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;16-18(17)15-10-14(11-6-2-1-3-7-11)12-8-4-5-9-13(12)15/h2*16-18H,1-15H2;1-10H

Upstream product

• 3923-52-2 1,1-diphenyl-2-propyn-1-ol 
• 2622-14-2 tricyclohexylphosphine 

Downstream Products

• 36621-70-2 carbonylchlorohydridobis(tricyclohexylphosphine)ruthenium(II) 

Relevant articles and documents

Hoveyda–Grubbs catalysts with an N→Ru coordinate bond in a six-membered ring. Synthesis of stable, industrially scalable, highly efficient ruthenium metathesis catalysts and 2-vinylbenzylamine ligands as their precursors

A novel and efficient approach to the synthesis of 2-vinylbenzylamines is reported. This involves obtaining 2-vinylbenzylamine ligands from tetrahydroisoquinoline by alkylation and reduction followed by the Hofmann cleavage. The resultant 2-vinylbenzyl-amines allowed us to obtain new Hoveyda–Grubbs catalysts, which were thoroughly characterised by NMR, ESIMS, and X-ray crystallography. The utility of this chemistry is further demonstrated by the tests of the novel catalysts (up to 10?2 mol %) in different metathesis reactions such as cross metathesis (CM), ring-closing metathesis (RCM) and ring-opening cross metathesis (ROCM).

Method for preparation of a ruthenium indenylidene complex

The present invention is directed to a method for the preparation of ruthenium catalyst (PCy3)2Cl2Ru(phenylindenylidene) (Umicore catalyst "M1"). The method comprises a one-step reaction reacting the precursor compound (PPh3)2Cl2Ru(3-phenylindenylidene) with PCy3 in a cyclic ether solvent (preferably THF) in concentrations in the range of 0.2 to 0.6 mol catalyst/I while simultaneously precipitating the product from the reaction mixture. A cyclic ether solvate product with high crystallinity and high purity is obtained.