2503-80-2 Usage
Description
MY 12-62c is a monohydroxyquinoline derivative with an additional heptyl substituent at position 2, which is an antibiotic metabolite produced from a marine pseudomonad.
Uses
Used in Pharmaceutical Industry:
MY 12-62c is used as an antibiotic agent for its antimicrobial properties, particularly against various types of bacteria. Its unique structure allows it to target and disrupt bacterial cell membranes, leading to cell death and preventing the growth of harmful microorganisms.
Used in Cosmetic Industry:
MY 12-62c is used as a preservative in cosmetic products for its antimicrobial properties, helping to prevent the growth of bacteria, fungi, and other microorganisms that can cause spoilage or contamination of the products.
Used in Agriculture:
MY 12-62c is used as a biopesticide in agriculture for its ability to control and eliminate harmful bacteria and fungi that can damage crops and reduce yield. Its targeted action against specific pathogens makes it a valuable tool in maintaining crop health and productivity.
Used in Water Treatment:
MY 12-62c is used in water treatment processes as a biocide to control the growth of bacteria, algae, and other microorganisms that can contaminate water supplies and pose health risks. Its effectiveness in eliminating harmful microorganisms helps to ensure the safety and quality of water for various uses.
Check Digit Verification of cas no
The CAS Registry Mumber 2503-80-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,0 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2503-80:
(6*2)+(5*5)+(4*0)+(3*3)+(2*8)+(1*0)=62
62 % 10 = 2
So 2503-80-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H21NO/c1-2-3-4-5-6-9-13-12-16(18)14-10-7-8-11-15(14)17-13/h7-8,10-12H,2-6,9H2,1H3,(H,17,18)
2503-80-2Relevant articles and documents
Chemical Modification and Detoxification of the Pseudomonas aeruginosa Toxin 2-Heptyl-4-hydroxyquinoline N-Oxide by Environmental and Pathogenic Bacteria
Thierbach, Sven,Birmes, Franziska S.,Letzel, Matthias C.,Hennecke, Ulrich,Fetzner, Susanne
, p. 2305 - 2312 (2017)
2-Heptyl-4-hydroxyquinoline N-oxide (HQNO), a major secondary metabolite and virulence factor produced by the opportunistic pathogen Pseudomonas aeruginosa, acts as a potent inhibitor of respiratory electron transfer and thereby affects host cells as well as microorganisms. In this study, we demonstrate the previously unknown capability of environmental and pathogenic bacteria to transform and detoxify this compound. Strains of Arthrobacter and Rhodococcus spp. as well as Staphylococcus aureus introduced a hydroxyl group at C-3 of HQNO, whereas Mycobacterium abscessus, M. fortuitum, and M. smegmatis performed an O-methylation, forming 2-heptyl-1-methoxy-4-oxoquinoline as the initial metabolite. Bacillus spp. produced the glycosylated derivative 2-heptyl-1-(β-d-glucopyranosydyl)-4-oxoquinoline. Assaying the effects of these metabolites on cellular respiration and on quinol oxidase activity of membrane fractions revealed that their EC50 values were up to 2 orders of magnitude higher than that of HQNO. Furthermore, cellular levels of reactive oxygen species were significantly lower in the presence of the metabolites than under the influence of HQNO. Therefore, the capacity to transform HQNO should lead to a competitive advantage against P. aeruginosa. Our findings contribute new insight into the metabolic diversity of bacteria and add another layer of complexity to the metabolic interactions which likely contribute to shaping polymicrobial communities comprising P. aeruginosa.
