251089-58-4

Basic information

• Product Name: 2-fluoro-6-methoxy-3,5-dinitro-benzoic acid methyl ester
• Synonyms: 2-fluoro-6-methoxy-3,5-dinitro-benzoic acid methyl ester
• CAS NO: 251089-58-4
• Molecular Weight: 274.162
• Mol File: 251089-58-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-fluoro-6-methoxy-3,5-dinitro-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-6-methoxy-3,5-dinitro-benzoic acid methyl ester(251089-58-4)
• EPA Substance Registry System: 2-fluoro-6-methoxy-3,5-dinitro-benzoic acid methyl ester(251089-58-4)

Safety Data

• Hazardous Substances Data: 251089-58-4(Hazardous Substances Data)

Upstream product

• 178747-79-0 methyl 2-fluoro-6-methoxybenzoate 

Downstream Products

• 286372-29-0 8-(1-benzenesulfonyl-4-{6-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-pent-3-enyl)-6-[(tert-butyl-dimethyl-silanyl)-amino]-7-(tert-butyl-dimethyl-silanyloxy)-4H-benzo[1,4]thiazin-3-one 
• 251089-84-6 8-(1-benzenesulfonyl-4-{6-[10-(tert-butyl-dimethyl-silanyloxy)-8-methoxy-deca-2,4,6-trienyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-pent-3-enyl)-6-[(tert-butyl-dimethyl-silanyl)-amino]-7-(tert-butyl-dimethyl-silanyloxy)-4H-benzo[1,4]thiazin-3-one 
• 251089-55-1 8-benzenesulfonylmethyl-6-[(tert-butyl-dimethyl-silanyl)-amino]-7-(tert-butyl-dimethyl-silanyloxy)-4H-benzo[1,4]thiazin-3-one 
• 251089-75-5 toluene-4-sulfonic acid 6-benzyloxycarbonylamino-7-methoxy-3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-8-ylmethyl ester 
• 251089-60-8 (8-benzenesulfonylmethyl-7-methoxy-3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-carbamic acid benzyl ester 
• 286372-25-6 6-benzyloxycarbonylamino-7-methoxy-3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-8-carboxylic acid methyl ester 
• 251089-74-4 (8-hydroxymethyl-7-methoxy-3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-carbamic acid benzyl ester 
• 251089-76-6 6-amino-8-benzenesulfonylmethyl-7-hydroxy-4H-benzo[1,4]thiazin-3-one 
• 165337-97-3 (+)-thiazinotrienomycin E 
• 286372-63-2 C₃₈H₅₁N₃SO₈C₂H₄O 
• 286372-23-4 2-methoxy-6-methoxycarbonylmethylsulfanyl-3,5-dinitro-benzoic acid methyl ester 

Relevant articles and documents

Total synthesis of the ansamycin antibiotic (+)-thiazinotrienomycin E

The first total synthesis of (+)-thiazinotrienomycin E (1), member of a novel class of cytotoxic ansamycin antibiotics, has been achieved. Key features of the synthetic strategy include (a) the efficient construction of sulfone 7 incorporating TBS protection of the aniline, (b) an improved synthesis of allyl chloride (-)-6, the advanced intermediate employed in our trienomycins A and F total syntheses, (c) application of the Kocienski modified Julia protocol to elaborate the E,E,E-triene subunit in a stereo- controlled fashion, (d) an efficient union of sulfone 7 with advanced iodide 62, and (e) Mukaiyama macrolactamization to access the thiazinotrienomycin macrocyclic ring.