251103-74-9Relevant articles and documents
A general synthesis of 1-(1-alkenyl)benzotriazoles
Pleynet, David P.M.,Dutton, Jonathan K.,Johnson, Peter A.
, p. 11903 - 11926 (2007/10/03)
1-Methyl, 1-(alkoxymethyl) and 1-(trimethylsilylmethyl)benzotriazoles are metallated at the α-carbon. Trapping of the resulting metallated species with chlorotrimethylsilane gives compounds which undergo Peterson olefination even with hindered ketones. In some cases, metallation at the 4-position of the benzotriazole is observed. An exhaustive metallation/silylation sequence gives 4-trimethylsilyl substituted 1-benzotriazoles in good yields.
