25165-80-4

Basic information

• Product Name: 2-((E)-((4-(trifluoromethyl)phenyl)imino)methyl)phenol
• Synonyms: 6-({[4-(trifluoromethyl)phenyl]amino}methylidene)cyclohexa-2,4-dien-1-one
• CAS NO: 25165-80-4
• Molecular Formula: C₁₄H₁₀F₃NO
• Molecular Weight: 265.2305
• Mol File: 25165-80-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 351.1°C at 760 mmHg
• Flash Point: 166.2°C
• Density: 1.413g/cm³
• Vapor Pressure: 4.2E-05mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: 2-((E)-((4-(trifluoromethyl)phenyl)imino)methyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((E)-((4-(trifluoromethyl)phenyl)imino)methyl)phenol(25165-80-4)
• EPA Substance Registry System: 2-((E)-((4-(trifluoromethyl)phenyl)imino)methyl)phenol(25165-80-4)

Safety Data

• Hazardous Substances Data: 25165-80-4(Hazardous Substances Data)

Usage

Type of compound

Organic

Functional groups

Phenolic group, trifluoromethyl group

Attachment to structure

Attached to a benzene ring

Usage

Building block in the synthesis of pharmaceuticals and agrochemicals

Potential properties

Anti-cancer

Applications

Materials science (organic electronic devices)

Upstream product

• 455-14-1 4-trifluoromethylphenylamine 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1360873-52-4 (3aS,4R,9aR)-N-(4-(trifluoromethyl)phenyl)-3,3a,4,9a-tetrahydro-2H-furo[2,3-b]chromen-4-amine 
• 1400665-64-6 bis[(N-salicylidene)-4-trifluoromethylanilinato]tin(II) 
• 1322617-57-1 N-(3-benzyl-2-oxo-4-(4-(trifluoromethyl)phenylamino)chroman-3-yl)benzamide 
• 1322617-56-0 N-(3-benzyl-2-oxo-4-(4-(trifluoromethyl)phenylamino)chroman-3-yl)benzamide 
• 1039041-44-5 [p-CF₃C₆H₄N=CH(C₆H₄O)]VCl₂(THF)2 

Relevant articles and documents

Influence of substituents on the structure of Schiff bases Cu(II) complexes

The relationship between molecular conformation and substituent effects of salicylaldehyde Schiff-base Cu(II) complexes was explored. For this study, eight samples of the complexes Cu(Sal-X)2 (X = OMe, Me, H, F, Cl, Br, CF3 and CN) w

AIPE-active platinum(ii) complexes with tunable photophysical properties and their application in constructing thermosensitive probes used for intracellular temperature imaging

Aggregation-induced phosphorescent emission (AIPE) luminogens based on phosphorescent transition metal complexes have many application advantages in bioimaging compared with fluorescent organic dyes because of their long excitation lifetime and reduced ph

Halide substituted Schiff-bases: Different activities in methyltrioxorhenium(VII) catalyzed epoxidation via different substitution patterns

This report shows the influence of halide substituted Schiff-bases as ligands of methyltrioxorhenium (MTO) in epoxidation catalysis. Therefore, selected Schiff-bases were prepared by the reaction of hydroxy-benzaldehydes and aniline derivates. These differently substituted Schiff-bases were tested as MTO-ligands in cyclooctene-and 1-octene-epoxidation. Although no great disparities among the substitution patterns have been found, some conclusions can be drawn. Flourines are inferior to chlorines or bromines as substituents. Halides in ortho-position lead to higher activities than in para-or meta-position. The balance between electron donating and withdrawing influences at the Schiff-base plays a prominent role in their utility as ligand to MTO in epoxidation catalysis.