25219-59-4

Basic information

• Product Name: 3-Methoxy-2-Piperidone
• Synonyms: 3-Methoxy-2-Piperidone;3-Methoxy-2-oxopiperidine;3-Methoxypiperidin-2-one;3-Methoxy-2-piperidione;2-Piperidinone,3-Methoxy-;3-Methoxy-2-piperidinone
• CAS NO: 25219-59-4
• Molecular Formula: C₆H₁₁NO₂
• Molecular Weight: 129.16
• EINECS: 1312995-182-4
• Mol File: 25219-59-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 279.963 °C at 760 mmHg
• Flash Point: 123.118 °C
• Appearance: /
• Density: 1.067 g/cm³
• Vapor Pressure: 0.00389mmHg at 25°C
• Refractive Index: 1.461
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 15.54±0.40(Predicted)
• CAS DataBase Reference: 3-Methoxy-2-Piperidone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methoxy-2-Piperidone(25219-59-4)
• EPA Substance Registry System: 3-Methoxy-2-Piperidone(25219-59-4)

Safety Data

• Hazardous Substances Data: 25219-59-4(Hazardous Substances Data)

Usage

Uses

3-Methoxypiperidin-2-one is a useful research chemical.

InChI:InChI=1/C6H11NO2/c1-9-5-3-2-4-7-6(5)8/h5H,2-4H2,1H3,(H,7,8)

Upstream product

• 67-56-1 methanol 
• 463362-69-8 3-diazo-piperidin-2-one 
• 4783-65-7 N-benzyl-2-piperidinone 
• 1215765-13-1 1-chloro-3-methoxypiperidin-2-one 
• 3184-13-2 L-ornithine hydrochloride 
• 1892-22-4 3-aminopiperidin-2-one 

Relevant articles and documents

Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents

A series of novel carbazole-containing amides and ureas were synthesized. A structure–activity relationship study of these compounds led to the identification of potent cryptochrome modulators. Based on the desired pharmacokinetic/pharmacodynamic parameters and the results of efficacy studies in db/db mice, compound 50 was selected for further profiling.

The synthesis and chemistry of 3-diazo-piperidin-2-one

The efficient synthesis of 3-diazo-piperidin-2-one, from L-ornithine, in two steps is reported. The chemistry of this new cyclic α-diazoamide was explored and allows the rapid access to a wide range of 3-substituted piperidin-2-one derivatives.