2525-85-1

Basic information

• Product Name: 1,1,2,2-TETRAFLUORO-1,4-DIPHENYLBUTANE-1,4-DIONE
• Synonyms: 1,1,2,2-TETRAFLUORO-1,4-DIPHENYLBUTANE-1,4-DIONE
• CAS NO: 2525-85-1
• Molecular Formula: C₁₆H₁₀F₄O₂
• Molecular Weight: 310.24
• Mol File: 2525-85-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 63-63.5 °C
• Boiling Point: 165-166 °C(Press: 0.58 Torr)
• Appearance: /
• Density: 1.318±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1,1,2,2-TETRAFLUORO-1,4-DIPHENYLBUTANE-1,4-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,2,2-TETRAFLUORO-1,4-DIPHENYLBUTANE-1,4-DIONE(2525-85-1)
• EPA Substance Registry System: 1,1,2,2-TETRAFLUORO-1,4-DIPHENYLBUTANE-1,4-DIONE(2525-85-1)

Safety Data

• Hazardous Substances Data: 2525-85-1(Hazardous Substances Data)

Usage

Class

Organic compound

Subclass

Ketones

Derivative

Fluorinated derivative of 1,4-diphenyl-1,4-diketone

Building block

Used for the synthesis of various organic compounds

Chemical structure

Two phenyl groups attached to a butane-1,3-dione skeleton with four fluorine atoms attached to the butane moiety

Potential applications

Pharmaceuticals, agrochemicals, and materials science

Unique properties

Chemical reactivity due to the presence of fluorine atoms and the dione structure

Upstream product

• 100-58-3 phenylmagnesium bromide 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 85914-80-3 2,2,3,3-tetrafluoro-1,4-diphenylbutane-1,4-diol 
• 327085-39-2 C₂₂H₂₈F₄O₂Si₂ 
• 679-13-0 perfluorosuccinic difluoride 
• 71-43-2 benzene 
• 86340-78-5 2,2-difluoro-1-phenyl-1-trimethylsiloxyethene 

Relevant articles and documents

New entry for fluorinated carbocycles: Unprecedented 3,6-disubstituted 1,1,2,2-tetrafluorocyclohexane derivatives

The synthetic protocols for symmetrical/unsymmetrical 3,6-disubstituted 1,1,2,2-tetrafluorocyclohexane molecules were successfully established for the first time. Some of thus obtained tetrafluorinated cyclohexanes underwent recrystallization to afford trans-configured products preferentially. One of the unsymmetrical trans-disubstituted tetrafluorocyclohexanes, trans-1-ethyl-2,2,3,3-tetrafluoro-4-[4-(trans-4-n-propylcyclohex-1-yl)phenyl]cyclohexane, was found to possess a low birefringence Δn (0.073) and a large negative dielectric anisotropy Δε (–9.4) in a binary mixture system, which were very prominent as characteristics of LC molecules in VA-mode driving LC displays.

Oxidative cross-coupling of ββ-difluoroenol silyl ethers with nucleophiles: A dipole-inversion method to difluoroketones

Oxidative cross-coupling of α-aryl-β,β-difluoroenol silyl ethers with heteroaromatics in the presence of Cu(OTf)2 in wet acetonitrile proceeds smoothly, affording heteroaryldifluoromethyl aryl ketones in 61-88% yields. Alcohols also react as nu

REDUCTION OF POLYFLUORINATED CARBONYL COMPOUNDS BY ETHOXYMAGNESIUM BROMIDE

The reduction of perfluoroalkyl phenyl ketones and diketones with ethoxymagnesium bromide takes place readily in the absence of branching at the α-carbon atom of the aliphatic radical and in the absence of a substituent or in the presence of only one orth