25250-77-5

Basic information

• Product Name: 1-(butylamino)propan-2-ol
• Synonyms: 1-(Butylamino)-2-propanol; 2-Propanol, 1-(butylamino)-
• CAS NO: 25250-77-5
• Molecular Formula: C₇H₁₇NO
• Molecular Weight: 131.216
• Mol File: 25250-77-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 211.7°C at 760 mmHg
• Flash Point: 72.9°C
• Density: 0.87g/cm³
• Vapor Pressure: 0.0405mmHg at 25°C
• Refractive Index: 1.437
• CAS DataBase Reference: 1-(butylamino)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(butylamino)propan-2-ol(25250-77-5)
• EPA Substance Registry System: 1-(butylamino)propan-2-ol(25250-77-5)

Safety Data

• Hazardous Substances Data: 25250-77-5(Hazardous Substances Data)

Usage

Type of compound

Tertiary amine alcohol

Structural components

Contains a butyl group and an amino group attached to a propan-2-ol backbone

Common uses

a. Solvent
b. Intermediate
c. Reagent in chemical reactions and processes

Applications

a. Pharmaceutical sector
b. Agricultural sector
c. Industrial sector

Safety precautions

a. Flammable
b. Potential for skin irritation
c. Potential for eye irritation
d. Potential for respiratory system irritation

Handling and storage

Handle and store with caution to prevent exposure and potential hazards

Upstream product

• 109-73-9 N-butylamine 
• 75-56-9 methyloxirane 
• 127-00-4 1-Chloro-2-propanol 

Downstream Products

• 1423166-13-5 2-butyl-5-((cyclohexylamino)methyl)-4-hydroxy-4-methyl-1,1-dioxo-isothiazolidine 
• 1423166-12-4 2-butyl-5-(4-fluorophenylthio-methyl)-4-hydroxy-4-methyl-1,1-dioxo-isothiazolidine 
• 51938-15-9 N-butyl-N-(2-oxopropyl)nitrosamine 
• 36652-84-3 1-[Butyl[2,6-dinitro-4-(trifluoromethyl)phenyl]amino]-2-propanol 

Relevant articles and documents

Syntheses of five- and seven-membered ring sultam derivatives by Michael addition and Baylis-Hillman reactions

Five- and seven-membered sultam derivatives were conveniently synthesized via intra- or intermolecular Michael additions and an improved vinyl sulfonamide Baylis-Hillman reaction. Two different cyclization pathways were explored for the oxa-Michael reaction. A good solvent was discovered for an otherwise sluggish ketone-type Baylis-Hillman reaction in which vinyl sulfonamide ketones were used as the precursors. Furthermore, a strong base caused vinyl sulfonamide ketones to undergo 5-endo-trig intramolecular cyclizations, which are disfavored according to Baldwin's rule. Finally Baylis-Hillman reaction products were used as scaffolds for diversity-oriented sultam syntheses.