25252-00-0

Basic information

• Product Name: 2-BROMO-5-IODOBENZOIC ACID
• Synonyms: 2-BROMO-5-IODOBENZOIC ACID;2-Bromo-5-iodobenzoic acid 97%
• CAS NO: 25252-00-0
• Molecular Formula: C₇H₄BrIO₂
• Molecular Weight: 326.91
• EINECS: -0
• Product Categories: Acids & Esters;Bromine Compounds;Iodine Compounds;C7;Carbonyl Compounds;Carboxylic Acids
• Mol File: 25252-00-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 171-175 °C
• Boiling Point: 371.2 °C at 760 mmHg
• Flash Point: 178.3 °C
• Appearance: /
• Density: 2.331 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 2.50±0.10(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2-BROMO-5-IODOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-IODOBENZOIC ACID(25252-00-0)
• EPA Substance Registry System: 2-BROMO-5-IODOBENZOIC ACID(25252-00-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 25252-00-0(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 124-38-9 carbon dioxide 
• 589-87-7 1,4-bromoiodobenzene 
• 88-65-3 2-bromobenzoic-acid 

Downstream Products

• 717880-58-5 2-bromo-5-iodobenzoic acid methyl ester 
• 1291094-59-1 (2-bromo-5-iodo-phenyl)-chroman-6-yl-methanone 
• 1291094-75-1 1-[6-(2-bromo-5-iodo-benzyl)-2,3-dihydro-benzo[1,4]oxazin-4-yl]-2,2,2-trifluoro-ethanone 
• 1291094-61-5 6-[2-bromo-5-((3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-2-yl)-benzyl]-chroman 
• 1291094-80-8 4-benzyl-6-[2-cyclopropyl-5-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-benzyl]-3,4-dihydro-2H-benzo[1,4]oxazine 
• 1291094-69-3 [(2R,3R,4R,5S,6S)-3,4,5-triacetoxy-6-[4-bromo-3-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)phenyl]tetrahydropyran-2-yl]methyl acetate 
• 946525-34-4 1-bromo-4-(1-methoxy-β-D-glucopyranosyl)-2-(phenoxymethyl)benzene 
• 762254-26-2 benzyl 2-bromo-5-cyanobenzoate 

Relevant articles and documents

Synthesis method of 2-halogen-5-iodobenzoic acid

The invention discloses a synthesis method of 2-halogen-5-iodobenzoic acid. The synthesis method comprises steps as follows: o-halogen benzoic acids are subjected to one-step iodo treatment in an iodio reagent, and 2-halogen-5-iodobenzoic acid is obtained. Aftertreatment comprises steps as follows: a reaction liquid is poured into a cold reductive water solution and quenched, a solvent is evaporated to dryness, recrystallization and filtration are performed, and a product can be obtained. The method is short in reaction route, simple to operate, environmentally friendly, safer and more economical and has broad application prospects.

Synthesis of dilactone bridged terphenyls with crankshaft architectures

Three highly fluorescent dilactone bridged terphenyls with crankshaft architectures have been synthesized. This general class of compounds is relatively unexplored. These compounds have been characterized by fluorescence and UV-vis spectroscopy. For all three compounds, a direct correlation between the rigidity of the terphenyl system and the strength of absorption and emission of light has been observed. Preliminary studies have indicated that compounds with this architecture have the potential to be useful as pH-driven molecular switches and/or sensors with instant fluorescence attenuation at high pH values.

Regioselective generation of aryllithiums from substituted bromobenzenes XC6H4Br (X = 4-Br, 4-I, 4-CN, 2-CN)

Selected activated bromobenzenes XC6H4Br (X = 4-Br, 4-I, 4-CN, 2-CN) were successfully deprotonated with lithium 2,2,6,6-tetramethylpiperidide (LTMP) in THF at -80°C. Thus, 2,5-dibromo-, 2-bromo-5-iodo-, 5-bromo-2-cyano-, and 3-bromo