252642-44-7

Basic information

• Product Name: 4-nitrobenzyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-1-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate
• Synonyms: 4-nitrobenzyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-1-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate
• CAS NO: 252642-44-7
• Molecular Weight: 475.522
• Mol File: 252642-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-nitrobenzyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-1-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitrobenzyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-1-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate(252642-44-7)
• EPA Substance Registry System: 4-nitrobenzyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-1-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate(252642-44-7)

Safety Data

• Hazardous Substances Data: 252642-44-7(Hazardous Substances Data)

Upstream product

• 141629-20-1 (S)-4-t-butyldimethylsilyloxy-1-methyl-2-oxopyrrolidine 
• 141629-21-2 (S)-4-hydroxy-1-methyl-2-oxopyrrolidine 
• 93711-81-0 (4-nitrophenyl)methyl (4R,5R,6S)-3-[(diphenoxyphosphinyl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 252642-40-3 (R)-3-mercapto-1-methyl-5-oxopyrrolidine 
• 252642-39-0 (R)-3-acetylthio-1-methyl-5-oxopyrrolidine 
• 252642-48-1 (S)-4-methanesulfonyloxy-1-methyl-2-oxopyrrolidine 

Downstream Products

• 162599-64-6 pivaloyloxymethyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-1-methyl-5-oxopyrrolidin-3-ylthio]-1-carbapen-2-em-3-carboxylate 

Relevant articles and documents

Synthesis and biological evaluation of new oral carbapenems with 1-methyl-5-oxopyrrolidin-3-ylthio moiety

The synthesis and biological properties of 1β-methylcarbapenems with 1-methyl-5-oxopyrrolidin-3-ylthio group at the C-2 position were studied. The sodium (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-1-methyl-5-oxopyrrolidin-3 -ylthio]-1-carbapen-2-em