253-45-2

Basic information

• Product Name: 2,7-Naphthyridine(7CI,8CI,9CI)
• Synonyms: 2,7-Naphthyridine(7CI,8CI,9CI);2,7-Naphthyridine;2,7-Diazanaphthalene
• CAS NO: 253-45-2
• Molecular Formula: C₈H₆N₂
• Molecular Weight: 130.15
• Product Categories: PYRIDINE
• Mol File: 253-45-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 96-97 °C
• Boiling Point: 286℃
• Flash Point: 108℃
• Appearance: /
• Density: 1.183
• Vapor Pressure: 0.00453mmHg at 25°C
• Refractive Index: 1.653
• Storage Temp.: 2-8°C
• PKA: 4.00±0.10(Predicted)
• CAS DataBase Reference: 2,7-Naphthyridine(7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,7-Naphthyridine(7CI,8CI,9CI)(253-45-2)
• EPA Substance Registry System: 2,7-Naphthyridine(7CI,8CI,9CI)(253-45-2)

Safety Data

• Hazardous Substances Data: 253-45-2(Hazardous Substances Data)

Usage

General Description

2,7-Naphthyridine, also known as 2,7-diazanonaphthalene, is a chemical compound with the molecular formula C9H6N2. It is a heterocyclic aromatic compound that is derived from naphthalene. 2,7-Naphthyridine has a variety of applications in the fields of organic synthesis and medicinal chemistry, where it is used as a building block for the synthesis of pharmaceuticals and other bioactive compounds. It exhibits antiviral, antimicrobial, and anticancer properties, making it a useful compound for drug discovery and development. Additionally, 2,7-Naphthyridine has been studied for its potential use in materials science, as it can be used as a ligand in coordination chemistry and for the synthesis of new functional materials. Overall, 2,7-Naphthyridine is a versatile compound with diverse applications in various scientific and industrial fields.

InChI:InChI=1/C8H6N2/c1-3-9-5-8-6-10-4-2-7(1)8/h1-6H

Upstream product

• 69042-30-4 1-chloro-[2,7]naphthyridine 
• 100135-62-4 3-Dicyanmethylen-glutarsaeure-diaethylester 
• 517-40-8 4-methyl-2,3-pyridinedicarboxylic acid 
• 853648-79-0 4-(2-hydroxy-ethyl)-nicotinic acid amide 
• 6790-32-5 3,4-dihydro-1H-pyrano[3,4-c]pyridin-1-one 
• 67988-50-5 2,7-naphthyridinyl-1(2H)-one 
• 3222-50-2 4-methylnicotinic acid 
• 154105-64-3 4-bromonicotinaldehyde 
• 1120-87-2 4-bromopyridin 
• 105-50-0 diethyl 1,3-acetonedicarboxylate 
• 222167-81-9 4-((trimethylsilyl)ethynyl)nicotinaldehyde 

Downstream Products

• 108749-08-2 1,2,3,4-tetrahydro-2,7-naphthyridine 

Relevant articles and documents

A rigid cavity containing tetra-cobalt(III) [2 × 2] grid complex

The synthesis and structure of a rigid, cavity containing tetra-cobalt(III) [2 × 2] grid complex using an unusual bis(bipyridine)dimethoxynaphthyridine ligand is described.

4-Piperidinecarboxamide modulators of vanilloid VR1 receptor

This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to hetero isonipecotic amides that are potent modulators of VR1 which are useful for the treatment and prevention of disease conditions in mammals.

The amination of halogeno-2,7- and 1,8-naphthyridines

The conversion of 1-halogeno-2,7-naphthyridines into the corresponding 1-amino compounds with KNH2/NH3, is shown, by the use of deuterated starting compounds, to proceed via an SN(AE)ipso substitution and not via an SN(AE)tele mechanism, even though convincing evidence for the formation of tele ?-adduct, 8-amino-1-halogeno-dihydro-2,7-naphthyridine, was obtained.Using the same methods, it is shown that the conversion of 2-bromo-1,8-naphthyridine into 2-amino-1,8-naphthyridine proceds, to the extent of 40percent via an odd SN(AE)tele pathway.