25327-36-0

Basic information

• Product Name: Benzeneacetic acid, a-(hydroxyimino)-, (Z)-
• CAS NO: 25327-36-0
• Molecular Formula: C8H7NO3
• Molecular Weight: 165.148
• Mol File: 25327-36-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-(hydroxyimino)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-(hydroxyimino)-, (Z)-(25327-36-0)
• EPA Substance Registry System: Benzeneacetic acid, a-(hydroxyimino)-, (Z)-(25327-36-0)

Safety Data

• Hazardous Substances Data: 25327-36-0(Hazardous Substances Data)

Upstream product

• 103-82-2 phenylacetic acid 
• 13665-04-8 2,2-dibromoacetophenone 
• 10349-06-1 3-phenylfurazan 
• 611-73-4 Benzoylformic acid 
• 31491-21-1 2-phenyl-1,1-bis(trimethylsilyloxy)ethene 
• 825-52-5 2-(hydroxyimino)-2-phenylacetonitrile 
• 4589-97-3 phenylglyoxime 
• 882750-37-0 phenyl-glyoxal-bis-(O-acetyl oxime ) 

Downstream Products

• 100-47-0 benzonitrile 
• 134837-12-0 3-phenyl-5-(n-pentyl)isoxazole 
• 2039-49-8 3,5-diphehylisoxazole 
• 17647-40-4 (+/-)-methyl 3-phenyl-5-methyl-4,5-dihydroisoxazole-5-carboxylate 
• 17669-30-6 dimethyl 3-phenyl-4,5-dihydroisoxazole-4,5-dicarboxylate 
• 54606-00-7 5-acetyl-4,5-dihydro-3-phenylisoxazole 
• 1011-38-7 4,5-dihydro-3-phenyl-5-isoxazolecarbonitrile 
• 17647-39-1 3-phenyl-4,5-dihydro-isoxazole-5-carboxylic acid methyl ester 
• 1037-05-4 5-(naphthalen-2-yl)-3-phenyl-4,5-dihydroisoxazole 
• 20822-00-8 5-(4-bromophenyl)-3-phenyl-4,5-dihydroisoxazole 
• 60579-19-3 5-(4-chlorophenyl)-3-phenyl-4,5-dihydroisoxazole 
• 20821-97-0 5-(4-methoxyphenyl)-3-phenyl-4,5-dihydroisoxazole 
• 4894-23-9 3,5-diphenyl-4,5-dihydro-isoxazole 
• 38113-96-1 methyl (Z)-2-(hydroxyimino)-2-phenylacetate 

Relevant articles and documents

Iron-Promoted Decarboxylation of Arylacetic Acids for the Synthesis of Aromatic Nitriles with Sodium Nitrite as the Nitrogen Source

A new and effective method was developed for the synthesis of aromatic nitriles from arylacetic acids by using NaNO 2as the nitrogen source and Fe(OTf) 3as the promoter at 50 °C. A series of arylacetic acids underwent this transformation to give the targeted products in yields of 51-90%. Because of the mild conditions, the reaction is compatible with a broad range of functional groups, including ester, carboxy, hydroxy, acetamido, halo, nitro, cyano, methoxy, and even highly reactive formyl groups.