2540-56-9

Basic information

• Product Name: 9(Z),11(E)-OCTADECADIENOIC ACID
• Synonyms: DELTA 9 CIS DELTA 11 TRANS OCTADECADIENOIC ACID;CLA 9C,11TR;CONJUGATED (9Z,11E)-LINOLEIC ACID;CONJUGATED LINOLEIC ACID (9Z,11E);BOVINIC ACID;13-OXO-9(Z),11(E)-OCTADECADIENOIC ACID;13-OXOODE;13-KETO-OCTADECA-9Z,11E-DIENOIC ACID
• CAS NO: 2540-56-9
• Molecular Formula: C₁₈H₃₂O₂
• Molecular Weight: 280.45
• Mol File: 2540-56-9.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 381.6 °C at 760 mmHg
• Flash Point: 278.5 °C
• Appearance: /
• Density: 0.911 g/cm³
• Vapor Pressure: 7.01E-07mmHg at 25°C
• Refractive Index: n20/D1.481
• Storage Temp.: −20°C
• PKA: 4.78±0.10(Predicted)
• CAS DataBase Reference: 9(Z),11(E)-OCTADECADIENOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 9(Z),11(E)-OCTADECADIENOIC ACID(2540-56-9)
• EPA Substance Registry System: 9(Z),11(E)-OCTADECADIENOIC ACID(2540-56-9)

Safety Data

• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 24-36/37-45
• RIDADR: UN 1230 3/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 2540-56-9(Hazardous Substances Data)

Usage

Description

9(Z),11(E)-OCTADECADIENOIC ACID, also known as Rumenic Acid, is an octadeca-9,11-dienoic acid with 9-cis,11-trans-stereochemistry. It is a trans fatty acid that has been found to possess potential health benefits, particularly in reducing the risk of cancer and cardiovascular diseases.

Uses

Used in Pharmaceutical Applications:
9(Z),11(E)-OCTADECADIENOIC ACID is used as a therapeutic agent for its potential to reduce the risk of cancer and cardiovascular diseases. It may also help in preventing disease processes that lead to chronic inflammation, atherosclerosis, and diabetes.
Used in Nutritional Supplements:
In the Nutrition Industry, 9(Z),11(E)-OCTADECADIENOIC ACID is used as an additive in nutritional supplements for its health-promoting properties, aiming to improve overall well-being and reduce the risk of various diseases.
Used in Research and Development:
In the Biomedical Research Industry, 9(Z),11(E)-OCTADECADIENOIC ACID is used as a subject of study for its potential applications in understanding and treating various diseases, including cancer and cardiovascular conditions.

Synthesis Reference(s)

Tetrahedron Letters, 27, p. 3745, 1986 DOI: 10.1016/S0040-4039(00)83869-1

InChI:InChI=1/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h7-10H,2-6,11-17H2,1H3,(H,19,20)/b8-7+,10-9-

Upstream product

• 2578-97-4 trans-ximenynic acid 
• 2462-85-3 linoleic acid methyl ester 
• 60-33-3 linoleic acid 
• 81212-19-3 (Z)-12-hydroxyoctadec-9-enoic acid 
• 55362-80-6 9-bromononan-1-ol 
• 41059-02-3 9-bromononanoic acid 
• 8001-23-8 safflower oil 
• 141-22-0 Ricinoleic acid 
• 540-12-5 ricinelaidic acid 
• 18829-56-6 (E)-2-Nonenal 
• 88462-46-8 (8-carboxyoctyl)triphenylphosphonium bromide 
• 112-53-8 1-dodecyl alcohol 
• 278181-50-3 (9Z,11E)-Octadeca-9,11-dienoic acid dodecyl ester 
• 56-23-5 tetrachloromethane 

Downstream Products

• 822-10-6 octadeca-9,11-dienoic acid methyl ester 
• 903581-73-7 octadeca-9t,11t-dienoyl chloride 
• 6114-22-3 9t,11t-octadecadienoic acid ethyl ester 
• 544-70-7 trans-9,trans-11-octadecadienoic acid 
• 87-93-4 9r_F,10t_F,11r'_F,12t'_F-tetrahydroxy-octadecanoic acid 
• 103281-90-9 8-(4-hexyl-9,10-dioxo-9,10-dihydro-[1]anthryl)-octanoic acid 
• 822-10-6 (9Z,11E)-methyl octadeca-9,11-dienoate 
• 119589-84-3 9,10;11,12-diepoxy-octadecanoic acid 
• 123-99-9 azelaic acid 
• 111-14-8 oenanthic acid 
• 872-23-1 (9E,11Z)-Octadeca-9,11-dienoic acid 
• 1002-79-5 (10E,12Z)-10,12-octadecadienoic acid methyl ester 
• 110331-79-8 18-vinyloxy-octadeca-7t,9t-diene 
• 215868-95-4 9,11-octadecadien-1-ol 

Relevant articles and documents

Revealing ruthenium and basicity synergetic effects in Ru-MgAl catalysts for isomerization of linoleic acid to conjugated linoleic acid

Ru-MgAl catalysts were prepared by co-precipitation at different pH values (x = 7-12), with the aims of investigating the effect of pH on their catalytic performance for isomerization of linoleic acid to conjugated linoleic acid and of understanding the relationship of basicity site and ruthenium activity site. The results showed that strong basicity and highly dispersed ruthenium may be the active sites for linoleic acid isomerization. Only if all three conditions, i.e., high Ru dispersion, appropriate SMSI effect and high number of strong basicity sites, are fulfilled can highly effective active sites be formed for the isomerization of linoleic acid to conjugated linoleic acid. A possible reaction mechanism for the isomerization was also proposed.

Synergetic effect of ruthenium and basicity sites in the Ru-MgAl catalyst for hydrogen-free production of conjugated linoleic acids

A series of Ru-MgAl composite oxide catalysts prepared by calcining the ruthenium grafted hydrotalcite-like precursor at various temperatures were used in the hydrogen-free production of conjugated linoleic acid. The effect of calcination temperature on the textural, base and catalytic properties of the materials was investigated. Results indicated that the Ru-MgAl composite oxides calcined at 450 °C showed high activity, namely, CLA productivity, CLA production rate and TOF up to 1.52 g CLA g (CLA) L-1 (solvent) min-1, 284 g (CLA) g-1 (Ru) h-1 and 102.6 mol (LA converted) mol-1 (Ru) h-1. Moreover, the biologically active CLA isomers, cis-9, trans-11, trans-10, cis-12 and trans-9, trans-11-CLA, were the main products, while almost no hydrogenated products were formed. Meanwhile, the role of ruthenium and basicity sites in the catalytic reaction has been studied. It was found that the basicity sites of the Ru-MgAl catalyst and the ruthenium activity sites seem to have a synergic effect on the catalytic reaction. The possible reaction mechanism for the isomerization was also proposed. This journal is

Method For The Production Of Conjugated Polyunsaturated Fatty Acids With Heterogenous Catalysts

The present invention relates to an improved process for the production of conjugated polyunsaturated fatty acids (PUFA), preferably conjugated linoleic acid (CLA), using finely dispersed heterogeneous metal catalysts on a mesoporous support, in the absence of Hg. The present invention also relates to a method to increase the large microporosity and (optionally) the small mesoporosity of a zeolite, thus obtaining a modified zeolite having a large and highly accessible internal surface.