25507-04-4 Usage
Description
Clindamycin palmitate is a water-soluble prodrug form of the antibiotic clindamycin . It undergoes rapid hydrolysis in vivo to release active clindamycin. Formulations containing clindamycin palmitate have been used in the treatment of various bacterial infections.
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 25507-04-4 differently. You can refer to the following data:
1. Clindamycin Palmitate is a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial.
2. antibacterial (tuberculostatic)
Brand name
Cleocin (Pharmacia & Upjohn).
General Description
Clindamycin palmitate hydrochloride (Cleocin Pediatric) isthe hydrochloride salt of the palmitic acid ester ofcleomycin. The ester bond is to the 2-hydroxyl group of thelincosamine sugar. The ester serves as a tasteless prodrugform of the antibiotic, which hydrolyzes to clindamycin inthe plasma. The salt form confers water solubility to theester, which is available as granules for reconstitution intoan oral solution for pediatric use. Although absorption of thepalmitate is slower than that of the free base, there is littledifference in overall bioavailability of the two preparations.Reconstituted solutions of the palmitate hydrochloride arestable for 2 weeks at room temperature. Such solutionsshould not be refrigerated because thickening occurs thatmakes the preparation difficult to pour.
Check Digit Verification of cas no
The CAS Registry Mumber 25507-04-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,5,0 and 7 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 25507-04:
(7*2)+(6*5)+(5*5)+(4*0)+(3*7)+(2*0)+(1*4)=94
94 % 10 = 4
So 25507-04-4 is a valid CAS Registry Number.
InChI:InChI=1/C34H63ClN2O6S.ClH/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-21-27(38)42-32-30(40)29(39)31(43-34(32)44-5)28(24(3)35)36-33(41)26-22-25(20-7-2)23-37(26)4;/h24-26,28-32,34,39-40H,6-23H2,1-5H3,(H,36,41);1H/t24-,25+,26-,28+,29+,30-,31+,32+,34+;/m0./s1