256373-96-3 Usage
Description
CP-456773 sodium is a chemical compound that has been utilized in various scientific research applications. It is known for its potential role in studying different biological processes and understanding the underlying mechanisms.
Usage:
Used in Neuroscience Research:
CP-456773 sodium is used as a research tool for studying the neuroprotective action of ketogenic diets. It aids in understanding the effects of such diets on brain health and function.
Used in Oncology Research:
In the field of oncology, CP-456773 sodium is used as a research compound to study the effect of inhibiting NLRP3 (nod-like receptor protein 3) inflammasome activity on tumor progression in mouse models. This helps in understanding the role of NLRP3 inflammasomes in cancer development and progression.
Used in Obstetrics and Gynecology Research:
CP-456773 sodium is also used in studying the cholesterol crystal-mediated IL-1b (interleukin-1b) response in placental explants. This application is crucial for understanding the role of cholesterol crystals in placental inflammation and its potential impact on pregnancy outcomes.
Biochem/physiol Actions
CP-456773 is known to inhibit the release of other proinflammatory cytokines such as IL-1α and IL-18. It is also referred to as MCC950.
Check Digit Verification of cas no
The CAS Registry Mumber 256373-96-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,6,3,7 and 3 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 256373-96:
(8*2)+(7*5)+(6*6)+(5*3)+(4*7)+(3*3)+(2*9)+(1*6)=163
163 % 10 = 3
So 256373-96-3 is a valid CAS Registry Number.
256373-96-3Relevant articles and documents
A synthesis of furan sulfonamide compounds useful in the synthesis of IL-1 inhibitors
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, (2008/06/13)
An efficent synthesis of furan sulfonamide compounds of formula ???comprising reacting a compound of formula II with a Grignard reagent in a reaction inert solvent, wherein R' is (C1-C6)alkyl. The compound of formula II is prepared by reacting a compound of formula III with a compound of formula IV wherein R' is (C1-C6)alkyl with a chorinating reagent and an acid scaverger in an inert solvent. The invention also includes a novel compound of the formula ???wherein R' is (C1-C6)alkyl and Q is halo, hydroxy or amino.
