2566-34-9Relevant articles and documents
A vitamin E derivative as a novel, extremely advantageous amino-protecting group
Rosenau,Chen,Habicher
, p. 8120 - 8121 (2007/10/02)
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Version: 1.0
Creation Date: Aug 11, 2017
Revision Date: Aug 11, 2017
Product name | 2-methyl-2-(methylamino)propanoic acid |
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Product number | - |
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Other names | 2-(Methylamino)-2-methylpropionic acid |
Identified uses | For industry use only. |
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Uses advised against | no data available |
Emergency phone number | - |
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Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
More Details:2566-34-9 SDS
methylamine hydrochloride
potassium cyanide
acetone
2-(methylamino)isobutyric acid
Conditions | Yield |
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With water at 50 - 55℃; im geschlossenen Gefaess und verseift man das entstandene α-Methylamino-isobuttersaeurenitril mit Salzsaeure; |
potassium cyanide
acetone
methylamine
2-(methylamino)isobutyric acid
Conditions | Yield |
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Verseifung des erhaltenen Nitrils; |
2-bromo-2-methylpropionic acid
methylamine
2-(methylamino)isobutyric acid
Conditions | Yield |
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at 100℃; | |
With water |
Conditions | Yield |
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With sodium hydroxide 1.) CH2Cl2, -20 deg C, 10 min, 2.) room temperature, 30 min, 3.) 70 deg C, 1 h; Yield given. Multistep reaction; |
2-(methylamino)isobutyric acid
chloroacetyl chloride
2-[(2-Chloro-acetyl)-methyl-amino]-2-methyl-propionic acid
Conditions | Yield |
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With hydroxide | 98% |
2-(methylamino)isobutyric acid
di-tert-butyl dicarbonate
N-tert-butoxycarbonyl-N-methyl-α-aminoisobutyric acid
Conditions | Yield |
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With tetramethyl ammoniumhydroxide In acetonitrile for 72h; Ambient temperature; | 95% |
2-(methylamino)isobutyric acid
3,5-diethoxy-4-pyridinecarboxyaldehyde
Conditions | Yield |
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In toluene for 0.183333h; Inert atmosphere; Reflux; | 95% |
Conditions | Yield |
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With dicyclohexyl-carbodiimide | 91.1% |
2-(methylamino)isobutyric acid
fullerene-C60
3,5-diethoxy-4-pyridinecarboxyaldehyde
N-methyl-2-(3,5-diethoxypyridin-4-yl)-5,5-dimethyl-fulleropyrrolidine of C60
Conditions | Yield |
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In toluene for 1h; Inert atmosphere; Reflux; | 80% |
[2,2]bipyridinyl
2-(methylamino)isobutyric acid
[CuII(bpy)(MAIB)]ClO4·H2O
Conditions | Yield |
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With triethylamine In methanol at 20℃; for 1h; | 77% |
Conditions | Yield |
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With triethylamine In methanol at 20℃; for 1h; Inert atmosphere; | 77% |
Conditions | Yield |
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In toluene for 0.25h; Inert atmosphere; Reflux; | 76% |
2-(methylamino)isobutyric acid
benzoyl chloride
N-benzoyl-N-methyl-α-amino-2-methylpropionic acid
Conditions | Yield |
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With sodium hydroxide for 2h; | 72.69% |
With pyridine; acetone |
2-(methylamino)isobutyric acid
thioacetic acid S-[4-(4-formyl-phenoxy)-butyl] ester
Conditions | Yield |
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In 1,2-dichloro-benzene at 145℃; for 0.3h; Inert atmosphere; | A 21% B 67% |
2-(methylamino)isobutyric acid
3,5-diethoxy-4-pyridinecarboxyaldehyde
Conditions | Yield |
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In toluene for 0.25h; Inert atmosphere; Reflux; | 64% |
Conditions | Yield |
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With ammonium hydroxide; [CuII(2,2'-bipyridine)(α-(methylamino)isobutyric acid(H-))]ClO4*H2O; dihydrogen peroxide In water; N,N-dimethyl-formamide at 35℃; Kinetics; | 47% |
With ammonium hydroxide; dihydrogen peroxide; copper dichloride In water; N,N-dimethyl-formamide at 35℃; Kinetics; Catalytic behavior; |
2-(methylamino)isobutyric acid
4-Ethynylbenzaldehyde
fullerene-C60
Conditions | Yield |
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In toluene for 12h; Inert atmosphere; Reflux; | 40% |
2-(methylamino)isobutyric acid
6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}hexanoic acid
Conditions | Yield |
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With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 1.5h; Inert atmosphere; | 30% |
2-(methylamino)isobutyric acid
Conditions | Yield |
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With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere; | 25% |
2-(methylamino)isobutyric acid
3-(3-(bromomethyl)-2-ethylphenyl)-5-(4-isopropoxy-3-(trifluoromethyl)-phenyl)-1,2,4-thiadiazole
2-((2-ethyl-3-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-thiadiazol-3-yl)benzyl)(methyl)amino)-2-methylpropanoic acid
Conditions | Yield |
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With potassium carbonate In N,N-dimethyl-formamide at 60℃; | 21% |
2-(methylamino)isobutyric acid
benzyl N-(4-aminophenethyl)-N-methyl-L-valinate dihydrochioride
N-[6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-N,2-dimethylalanine
Conditions | Yield |
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With triethylamine In dichloromethane at 20℃; for 3h; | 16% |
Conditions | Yield |
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With diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 5℃; Inert atmosphere; | A 15% B 13% |
Conditions | Yield |
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With triethylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 18h; Schlenk technique; | 15% |
2-(methylamino)isobutyric acid
α-(benzyloxycarbonyl-methyl-amino)-isobutyric acid
Conditions | Yield |
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With sodium hydroxide; benzyl chloroformate |
Conditions | Yield |
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With acetic acid |
Conditions | Yield |
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With acetic acid |
2-(methylamino)isobutyric acid
2-methoxy-phenylamine
N-(2-Methoxy-phenyl)-2-methyl-2-methylamino-propionamide
Conditions | Yield |
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(i) SOCl2, DMF, (ii) /BRN= 386210/; Multistep reaction; |
2-(methylamino)isobutyric acid
p-toluidine
2-Methyl-2-methylamino-N-p-tolyl-propionamide
Conditions | Yield |
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(i) SOCl2, DMF, (ii) /BRN= 471281/; Multistep reaction; |
2-(methylamino)isobutyric acid
aniline
2-Methyl-2-methylamino-N-phenyl-propionamide
Conditions | Yield |
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(i) SOCl2, DMF, (ii) /BRN= 605631/; Multistep reaction; |
2-(methylamino)isobutyric acid
2-Chloroaniline
N-(2-Chloro-phenyl)-2-methyl-2-methylamino-propionamide
Conditions | Yield |
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(i) SOCl2, DMF, (ii) /BRN= 606077/; Multistep reaction; |
2-(methylamino)isobutyric acid
1-amino-3-methylbenzene
2-Methyl-2-methylamino-N-m-tolyl-propionamide
Conditions | Yield |
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(i) SOCl2, DMF, (ii) /BRN= 635944/; Multistep reaction; |
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