2576-67-2

Basic information

• Product Name: H-GLY-LEU-GLY-OH
• Synonyms: ((2-[(Aminoacetyl)amino]-4-methylpentanoyl)amino)acetic acid;Glycine, N-(N-glycyl-L-leucyl)-;GLYCYL-L-LEUCINYL-GLYCINE;GLYCYL-L-LEUCYLGLYCINE;H-GLY-LEU-GLY-OH;N-(N-glycyl-L-leucyl)glycine;Gly-Leu-Gly-OH;Gly-L-Leu-Gly-OH
• CAS NO: 2576-67-2
• Molecular Formula: C₁₀H₁₉N₃O₄
• Molecular Weight: 245.28
• EINECS: 219-925-8
• Product Categories: Biochemistry;Oligopeptides;Peptide Synthesis
• Mol File: 2576-67-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 573.7°Cat760mmHg
• Flash Point: 300.8°C
• Appearance: /
• Density: 1.199g/cm³
• Vapor Pressure: 1.17E-14mmHg at 25°C
• Refractive Index: 58 ° (C=5, H2O)
• Storage Temp.: -15°C
• PKA: 3.28±0.10(Predicted)
• CAS DataBase Reference: H-GLY-LEU-GLY-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-GLY-LEU-GLY-OH(2576-67-2)
• EPA Substance Registry System: H-GLY-LEU-GLY-OH(2576-67-2)

Safety Data

• Hazardous Substances Data: 2576-67-2(Hazardous Substances Data)

Usage

General Description

H-GLY-LEU-GLY-OH is a peptide consisting of three amino acids in the sequence glycine-leucine-glycine. Glycine is the simplest amino acid and is nonpolar, while leucine is a hydrophobic amino acid. When combined, these three amino acids form a peptide with potential biological and pharmacological activities. Peptides like H-GLY-LEU-GLY-OH are important building blocks for proteins and play a role in various biological processes, including cell signaling and immune response. Due to its unique sequence, H-GLY-LEU-GLY-OH may have specific functions and potential applications in research and medicine.

InChI:InChI=1/C10H19N3O4/c1-6(2)3-7(13-8(14)4-11)10(17)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,17)(H,13,14)(H,15,16)

Upstream product

• 27560-15-2 methyl 2-(2-amino-4-methylpentanamido)acetate 
• 1421-69-8 (S)-2-(2-Benzyloxycarbonylamino-acetylamino)-4-methyl-pentanoic acid 
• 102895-76-1 N-benzoyloxycarbonylglycyl-L-leucylglycine benzylester 
• 7325-21-5 glycyl-L-leucylglycylglycine 
• 16816-39-0 N-[N-(N-benzyloxycarbonyl-glycyl)-L-leucyl]-glycine methyl ester 

Downstream Products

• 16295-42-4 N-{N-[N-(N-benzyloxycarbonyl-glycyl)-glycyl]-L-leucyl}-glycine 
• 98282-21-4 benzoyl-Gly-Leu-Gly 

Relevant articles and documents

Thermodynamic Properties of Peptide Solutions Part 6. The Amino Acid Side-chain Contributions to the Partial Molar Volumes and Heat Capacities of some Tripeptides in Aqueous Solution

Limiting partial molar volumes, V02, and partial molar heat capacities, C0p,2, have been determined for the tripeptides glycyl-L-valylglycine, glycyl-DL-serylglycine and the D and L isomers of glycylleucylglycine in aqueous solution at 298.15 K.These V02 and C0p,2 results, in conjunction with those for glycylglycylglycine, were used to estimate the contribution of the side chains to the thermodynamic properties.The results obtained are compared with those estimated using V02 and C0p,2 data for amino acids and dipeptides.The comparison suggests that the tripeptides of sequence glycyl-X-glycine are reasonable models for estimating the contribution to the thermodynamic properties of proteins made by solvent-accessible side chains.