25830-78-8

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-(tetrahydro-2,6-dioxo-2H-pyran-3-yl)-, (R)-
• CAS NO: 25830-78-8
• Molecular Formula: C13H9NO5
• Molecular Weight: 259.218
• Mol File: 25830-78-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-(tetrahydro-2,6-dioxo-2H-pyran-3-yl)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-(tetrahydro-2,6-dioxo-2H-pyran-3-yl)-, (R)-(25830-78-8)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-(tetrahydro-2,6-dioxo-2H-pyran-3-yl)-, (R)-(25830-78-8)

Safety Data

• Hazardous Substances Data: 25830-78-8(Hazardous Substances Data)

Usage

Molecular class

Isoindole-1,3-diones

Structural feature

Tetrahydro-2,6-dioxo-2H-pyran-3-yl group

Stereochemistry

R configuration at the stereocenter

Potential applications

Organic synthesis, pharmaceutical research

Safety precautions

Handle with care, follow proper safety procedures due to potential hazards.

Upstream product

• 85-44-9 phthalic anhydride 
• 6893-26-1 D-Glutamic acid 
• 22911-88-2 (R)-2-phthalimidoglutaric acid 
• 22509-74-6 N-ethoxycarbonylphthalimide 

Downstream Products

• 53987-25-0 N-phthaloyl-L-glutamic acid-γ-p-biphenylmethyl ester 
• 7390-76-3 (R)-2-amino-6-diazo-5-oxo-hexanoic acid 
• 124078-89-3 (2S,3aS,7aS)-1-(N-benzyloxycarbonyl-L-phenylalanyl-γ-D-glutamyl)-octahydro-1H-indole-2-carboxylic acid 
• 124078-89-3 (2S,3aS,7aS)-1-[(R)-4-((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-4-carboxy-butyryl]-octahydro-indole-2-carboxylic acid 
• 124078-71-3 (2S,3aS,7aS)-1-(L-phenylalanyl-γ-D-glutamyl)octahydro-1H-indole-2-carboxylic acid 
• 124078-71-3 (2S,3aS,7aS)-1-[(R)-4-((R)-2-Amino-3-phenyl-propionylamino)-4-carboxy-butyryl]-octahydro-indole-2-carboxylic acid 
• 116586-22-2 (2S,3aS,7aS)-1-[(R)-4-((S)-2-Benzyloxycarbonylamino-6-tert-butoxycarbonylamino-hexanoylamino)-4-carboxy-butyryl]-octahydro-indole-2-carboxylic acid 
• 127413-74-5 (2S,3aS,7aS)-1-[(R)-4-((S)-2-Benzyloxycarbonylamino-4-carbamoyl-butyrylamino)-4-carboxy-butyryl]-octahydro-indole-2-carboxylic acid 
• 127413-77-8 (2S,3aS,7aS)-1-[(R)-4-((S)-2-Benzyloxycarbonylamino-4-carboxy-butyrylamino)-4-carboxy-butyryl]-octahydro-indole-2-carboxylic acid 
• 116587-12-3 (2S,3aS,7aS)-1-[(R)-4-((S)-5-Amino-2-benzyloxycarbonylamino-pentanoylamino)-4-carboxy-butyryl]-octahydro-indole-2-carboxylic acid 
• 127413-75-6 (2S,3aS,7aS)-1-{(R)-4-[((S)-1-Benzyloxycarbonyl-pyrrolidine-2-carbonyl)-amino]-4-carboxy-butyryl}-octahydro-indole-2-carboxylic acid 
• 127413-76-7 (2S,3aS,7aS)-1-[(R)-4-(2-Benzyloxycarbonylamino-acetylamino)-4-carboxy-butyryl]-octahydro-indole-2-carboxylic acid 
• 116587-09-8 (2S,3aS,7aS)-1-(N²-benzyloxycarbonyl-L-lysyl-γ-D-glutamyl)octahydro-1H-indole-2-carboxylic acid 

Relevant articles and documents

Poly-γ-p-Biphenylmethyl-Glutamate as Enantiodifferentiating Alignment Medium for NMR Spectroscopy with Temperature-Tunable Properties

The use of anisotropic NMR parameters—especially residual dipolar couplings (RDCs)—offers access to additional structural information and, therefore, alignment media required for this approach are under a continuous development. Here, we present poly-γ-p-biphenylmethyl-glutamate (PBPMG) as a new versatile enantiodifferentiating alignment medium. The thermoresponsive properties of this polymer allowed for RDC measurements of more than one orientation within the same sample at different temperatures. Moreover, the outstanding enantiodifferentiation along with excellent spectral quality even offered the opportunity to differentiate enantiomers in mixtures.