258854-17-0Relevant articles and documents
Protein and peptide-free synthetic vaccines against streptococcus pneumoniae type 3
-
Paragraph 0117, (2015/03/31)
The present invention provides a protein- and peptide-free conjugate comprising a synthetic carbohydrate and a carrier molecule, wherein the synthetic carbohydrate is a Streptococcus pneumoniae type 3 capsular polysaccharide related carbohydrate and the carrier molecule is a glycosphingolipid. Said conjugate and pharmaceutical composition thereof are useful for immunization against diseases associated with Streptococcus pneumoniae, and more specifically against diseases associated with Streptococcus pneumoniae type 3.
CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES
-
Paragraph 0242, (2015/09/28)
The present invention relates to the field of synthesizing and biologically evaluating of a novel class of carbohydrate-based vaccines. The new vaccines consist of a multi-modular structure which allows applying the vaccine to a whole variety of pathogenes. This method allows preparing vaccines against all pathogens expressing immunogenic carbohydrate antigens. As conjugation of antigenic carbohydrates to proteins is not required the conjugate vaccine is particularly heat stable. No refrigeration is required, a major drawback of protein-based vaccines.
Novel sulfofucosylacylglycerol derivatives and use thereof as medicaments
-
, (2008/06/13)
Novel sulfofucosylacylglycerol derivatives represented by General Formula (1): 1where R101 represents an acyl residue of a higher fatty acid and R102 represents a hydrogen atom or an acyl residue of a higher fatty acid. The derivati