260997-31-7

Basic information

• Product Name: (E)-(R)-3-((R)-1-Phenyl-ethylamino)-hept-5-enoic acid isopropyl ester
• Synonyms: (E)-(R)-3-((R)-1-Phenyl-ethylamino)-hept-5-enoic acid isopropyl ester
• CAS NO: 260997-31-7
• Molecular Weight: 289.418
• Mol File: 260997-31-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-(R)-3-((R)-1-Phenyl-ethylamino)-hept-5-enoic acid isopropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(R)-3-((R)-1-Phenyl-ethylamino)-hept-5-enoic acid isopropyl ester(260997-31-7)
• EPA Substance Registry System: (E)-(R)-3-((R)-1-Phenyl-ethylamino)-hept-5-enoic acid isopropyl ester(260997-31-7)

Safety Data

• Hazardous Substances Data: 260997-31-7(Hazardous Substances Data)

Upstream product

• 260997-21-5 isopropyl (2E,5E)-hepta-2,5-dienoate 

Downstream Products

• 260997-26-0 (4R,6R,1'S,αR)-3-(α-methylbenzyl)-4-(isopropoxycarbonylmethyl)-6-(1'-iodoethyl)-1,3-oxazin-2-one 
• 260997-29-3 (4R,6R,1'R,αR)-3-(α-methylbenzyl)-4-(isopropoxycarbonylmethyl)-6-(1'-aminoethyl)-1,3-oxazin-2-one 
• 260997-24-8 (3R,5E,αR)-isopropyl 3-(N-benzyloxycarbonyl-N-α-methylbenzylamino)hept-5-enoate 

Relevant articles and documents

Asymmetric synthesis of a highly functionalized β-amino acid: The key amino acid of sperabillins B and D

The asymmetric synthesis of the highly functionalized (3R,5R,6R)-3,6-diamino-5-hydroxyheptanoic acid, the key amino acid fragment of sperabillins B and D, was achieved by an asymmetric Michael addition of lithium (R)-(α-methylbenzyl)allylamide 10 to (E,E)-2,5-heptadienoate establishing the C-3 stereogenic centre, the information from which was propagated to the C-5 and C-6 centres by a highly stereoselective iodocyclocarbamation reaction.