26121-45-9

Basic information

• Product Name: (E)-4-phenyl-3-butenamide
• Synonyms: (E)-4-phenyl-3-butenamide
• CAS NO: 26121-45-9
• Molecular Weight: 161.203
• Mol File: 26121-45-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (E)-4-phenyl-3-butenamide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-phenyl-3-butenamide(26121-45-9)
• EPA Substance Registry System: (E)-4-phenyl-3-butenamide(26121-45-9)

Safety Data

• Hazardous Substances Data: 26121-45-9(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 85669-63-2 (E)-cinnamyl diethyl phosphate 
• 7217-71-2 1-phenyl-2-propenyl acetate 
• 77287-34-4 formamide 
• 144-48-9 iodacetamide 
• 103-64-0 bromostyrene 
• 25316-59-0 benzyl tri-n-butylammonium bromide 
• 79-06-1 2-propenamide 
• 2243-53-0 trans-styrylacetic acid 
• 118575-70-5 trans-styrylacetyl chloride 
• 21040-45-9 Cinnamyl acetate 
• 21087-29-6 trans-3-phenylprop-2-enyl chloride 
• 87802-71-9 (E)-methyl cinnamyl carbonate 

Downstream Products

• 1396722-90-9 (E)-4-phenylbut-3-enethioamide 
• 1199-98-0 4-phenylbutyramide 
• 7515-38-0 (E)-4-phenylbut-3-en-1-amine 
• 2243-53-0 trans-styrylacetic acid 

Relevant articles and documents

Nickel/Photo-Cocatalyzed C(sp2)-H Allylation of Aldehydes and Formamides

Herein we report a nickel/photo-cocatalyzed C(sp2)-H allylation of aldehydes and formamides wherein both allyl acetates and allyl alcohols can be used as the allylating agents. In this reaction, radical-type umpolung of the formyl moiety is enabled by tetrabutylammonium decatungstate as a hydrogen-atom-transfer photocatalyst, whereas nickel serves to cleave the C-O bond of allyl acetates or allyl alcohols. The synergistic effect of these two catalysts provides new access to various β,γ-unsaturated ketones and amides with high selectivities.

Synthesis of α-Arylcarboxylic acid amides from silyl enol ether via migratory Amidation with 2-azido-1,3-dimethylimidazolinium hexafluorophosphate

α-Arylcarboxylic acid amides were synthesized by reacting silyl enol ethers of aryl ketones and 2-azido-1,3-dimethylimidazolinium hexafluorophosphate (ADMP,1). Silyl enol ethers react with ADMP 1 to give N-(α-arylacyl) guanidines via the migration of aryl groups in enol ethers. The products were transformed to the corresponding α-aryl acetamides by treating with LiAlH4.

Synthesis of allylamides from allyl halides, carbon monoxide, and titanium-nitrogen complexes prepared from molecular nitrogen

4-Phenylbut-3-enamide could be synthesized from corresponding 3-chloroprop-2-enylbenzene, carbon monoxide (1atm), and titanium-nitrogen complexes, prepared from Ti(OiPr)4, Li, TMSCl, and molecular nitrogen (1atm), using a palladium catalyst. The reaction proceeds via transmetalation of the titanium-nitrogen complex to an acylpalladium complex. PtBu3 as a ligand of the palladium catalyst, afforded a good result, and the amounts of Li and TMSCl affected the yield of amide. When the reaction was carried out using a bidentate ligand on the palladium complex under an atmosphere of argon instead of carbon monoxide, an allylamine derivative was obtained.