261511-10-8Relevant articles and documents
N-(1-Benzotriazol-1-ylalkyl)amides, Versatile α-Amidoalkylation Reagents. 1. α-Amidoalkylation of CH Acids
Katritzky, Alan R.,Pernak, Juliusz,Fan, Wei-Qiang,Saczewski, Franciszek
, p. 4439 - 4443 (2007/10/02)
N-(1-Benzotriazol-1-ylalkyl)amides 2, easily prepared from an amide and an aldehyde with benzotriazole, react smoothly with CH acids under mild conditions to give the α-amidoalkylation products in good yields.Benzotriazole aminals also react with CH acids in the presence of methyl iodide.