2629-11-0 Usage
Uses
Used in Pharmaceutical Industry:
(13α,17aα)-7α-(Acetyloxy)-14β,15β:21,23-diepoxy-4,4,8-trimethyl-D-homo-24-nor-17-oxa-5α-chola-20,22-diene-3,16-dione is used as a potent synthetic corticosteroid for its anti-inflammatory and immunosuppressive properties. It is particularly effective in the treatment of inflammatory diseases and autoimmune disorders due to its ability to regulate metabolism and maintain electrolyte balance.
Used in Research and Development:
(13α,17aα)-7α-(Acetyloxy)-14β,15β:21,23-diepoxy-4,4,8-trimethyl-D-homo-24-nor-17-oxa-5α-chola-20,22-diene-3,16-dione is used as a target for further research and development in the pharmaceutical field. Its unique four-ring structure and complex chemical composition make it an interesting subject for studies aimed at understanding its pharmacological activity and potential applications in the treatment of various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 2629-11-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,2 and 9 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2629-11:
(6*2)+(5*6)+(4*2)+(3*9)+(2*1)+(1*1)=80
80 % 10 = 0
So 2629-11-0 is a valid CAS Registry Number.
InChI:InChI=1/C28H36O7/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)34-23(31)22-28(26,35-22)27(17,20)6/h9,12,14,17-18,20-22H,7-8,10-11,13H2,1-6H3/t17-,18+,20-,21+,22?,25-,26+,27+,28?/m1/s1
2629-11-0Relevant articles and documents
The Synthesis of a 1α,2α,3α-Triacetoxy Limonoid
Kehrli, Anne R. H.,Taylor, David A. H.,Niven, Margaret
, p. 2057 - 2065 (2007/10/02)
The report that Meerwein-Ponndorf reduction of gedunin (1a) gives 3α-hydroxy-3-deoxogedunin (2a) is wrong; the product is the 3β-epimer (2b). 3α-Acetoxy-7-deacetoxy-3-deoxo-7-oxgedunin (3c) was prepared by a stereospecific synthesis from cedrolide (1b), 7-deacetoxy-7-oxogedunin; osmium tetroxide oxidation then gave the 1,2α-glycol, isolated as the acetate (4a).Similarly, oxidation of the 3β-alcohol (3b) also gave the α-oriented glycol, as anticipated from the steric hindrance of the β-face of the molecule.Oxidation of the allylic alcohols (2b) or (3b), or of the allylic acetate (2d) with perbenzoic acid also takes place from the α-face of the molecule, giving the corresponding α-oxides (5a-c).The oxidation is pH sensitive; with a benzoate buffer the 7-oxo group in alcohol (3b) undergoes Baeyer-Villiger oxidation, giving the ε-lactone isolated as the acetate (6a).Opening of the oxide ring in the 3β,7α-diacetoxy oxide (5c) is complex.Identification of the products shows that the reaction involves participation by both the acetate groups.In contrast the 3β-acetoxy-7-oxo compound (5d) and the ε-lactone (6a) give the products of ring opening with assistance from the neighbouring acetate group, while the 3β-hydroxy compound (5b) gives the simple bromohydrin.
