26294-41-7 Usage
Description
Ipalbidine is an indolizine alkaloid found in the seeds of Ipomoea alba L., commonly known as moonflower. It forms colorless crystals and crystalline salts, such as the hydrochloride, picrate, and methiodide. The structure of ipalbidine has been confirmed through spectroscopic data.
Uses
1. Used in Pharmaceutical Industry:
Ipalbidine is used as a pharmaceutical compound for its potential therapeutic applications. The alkaloid's unique structure and properties make it a promising candidate for the development of new drugs and treatments.
2. Used in Chemical Research:
Ipalbidine serves as a valuable subject for chemical research, particularly in the study of indolizine alkaloids and their potential applications in various fields.
3. Used in Organic Chemistry:
Ipalbidine can be utilized as a starting material or intermediate in the synthesis of other organic compounds, contributing to the advancement of organic chemistry.
4. Used in Crystallography:
The formation of colorless crystals and crystalline salts by ipalbidine makes it an interesting subject for crystallographic studies, which can provide insights into the structural properties of similar compounds.
5. Used in Spectroscopy:
The spectroscopic data obtained from ipalbidine can be used to improve the understanding of the structure and properties of indolizine alkaloids, as well as to develop new techniques and methods in spectroscopy.
References
Gourley et al., Chem. Commun., 709 (1969)
Check Digit Verification of cas no
The CAS Registry Mumber 26294-41-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,2,9 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 26294-41:
(7*2)+(6*6)+(5*2)+(4*9)+(3*4)+(2*4)+(1*1)=117
117 % 10 = 7
So 26294-41-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H19NO/c1-11-9-13-3-2-8-16(13)10-15(11)12-4-6-14(17)7-5-12/h4-7,13,17H,2-3,8-10H2,1H3
26294-41-7Relevant articles and documents
Superacid-promoted synthesis of indolizidine derivatives
Kennedy, Sean,Kethe, Anila,Qarah, Ahmad,Klumpp, Douglas A.
, p. 1932 - 1935 (2018/04/16)
A series of amido-acetals were reacted with the Br?nsted superacid, CF3SO3H, to provides indolizidine derives by a cyclization cascade. A mechanism is proposed involving formation of a vinylogous enol which undergoes a 6π-electrocycl
A synthesis of (±)-ipalbidine using sulfur-controlled 6-exo selective radical cyclization of α-phenylthio amide
Ikeda, Masazumi,Shikaura, Jiro,Maekawa, Noriko,Daibuzono, Kaori,Teranishi, Hirotaka,Teraoka, Yoshiko,Oda, Norio,Ishibashi, Hiroyuki
, p. 31 - 34 (2007/10/03)
A synthesis of (±)-ipalbidine (1) has been achieved using Bu3SnH- mediated 6-exo selective radical cyclization of 2-[3-(phenylthio)prop-2- enyl]-N-[α(p-methoxyphenyl)-α-(phenylthio)acetyl]pyrrolidine (15) as a key step.
A Concise Total Synthesis of (+/-)-Ipalbidine by Application of the Aldimine-Diene Cyclocondensation Reaction
Danishefsky, Samuel J.,Vogel, Claus
, p. 3915 - 3916 (2007/10/02)
The scope of the diene-imine cyclocondensation reaction has been extended to the unstable Δ1-pyrroline.Cyclocondensation of this compound with the silylketene acetal derived from ethyl 2-p-anisyl-3-methylcrotonate provides the basis for a rapid
