263015-68-5 Usage
Chemical Class
Thiazole
Derivative
Thiazole-4-carboxylic acid derivative
Functional Group
Ethyl ester
Chlorine Content
Two chlorine atoms on the benzyl group
Electronegativity
High due to the presence of chlorine atoms
Reactivity
Potentially reactive
Biological Activities
Antifungal, antibacterial, and anticancer properties
Synthesis Utility
Suitable for use in the synthesis of other organic molecules due to its ability to undergo esterification reactions
Potential Applications
Pharmaceuticals, agrochemicals, and other fields
Check Digit Verification of cas no
The CAS Registry Mumber 263015-68-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,3,0,1 and 5 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 263015-68:
(8*2)+(7*6)+(6*3)+(5*0)+(4*1)+(3*5)+(2*6)+(1*8)=115
115 % 10 = 5
So 263015-68-5 is a valid CAS Registry Number.
263015-68-5Relevant articles and documents
A catch-and-release strategy for the combinatorial synthesis of 4-acylamino-1,3-thiazoles as potential CDK5 inhibitors
Larsen, Scott D.,Stachew, Carl F.,Clare, Paula M.,Cubbage, Jerry W.,Leach, Karen L.
, p. 3491 - 3495 (2007/10/03)
Two-dimensional libraries of 4-acylamino-1,3-thiazoles 9 were prepared via Curtius rearrangement of 1,3-thiazole-4-carbonyl azides 6, trapping of the intermediate isocyanates with oxime resin, and thermal regeneration of the isocyanates from the washed resin in the presence of nucleophiles. Several compounds proved to be selective inhibitors of CDK5/p25 versus the closely homologous CDK2/cyclin A enzyme, with the best analogue (43) possessing over 100-fold selectivity.
