264621-69-4

Basic information

• Product Name: 4-Oxazolidinecarboxylicacid,2-oxo-,ethylester,(4S)-(9CI)
• Synonyms: 4-Oxazolidinecarboxylicacid,2-oxo-,ethylester,(4S)-(9CI)
• CAS NO: 264621-69-4
• Molecular Formula: C₆H₉NO₄
• Molecular Weight: 159.14
• Product Categories: CARBOXYLICESTER
• Mol File: 264621-69-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Oxazolidinecarboxylicacid,2-oxo-,ethylester,(4S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxazolidinecarboxylicacid,2-oxo-,ethylester,(4S)-(9CI)(264621-69-4)
• EPA Substance Registry System: 4-Oxazolidinecarboxylicacid,2-oxo-,ethylester,(4S)-(9CI)(264621-69-4)

Safety Data

• Hazardous Substances Data: 264621-69-4(Hazardous Substances Data)

Upstream product

• 4117-31-1 ethyl L-serinate 
• 124-38-9 carbon dioxide 
• 104055-46-1 C₅H₁₁NO₃*(x)ClH 
• 332-25-2 4-(trifluoromethoxy)benzonitrile 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 264621-77-4 ethyl (4S)-3-but-3-enyl-2-oxooxazolidine-4-carboxylate 
• 264621-78-5 but-3-enyl (4S)-3-but-3-enyl-2-oxooxazolidine-4-carboxylate 
• 311310-18-6 (4S,2'R)-4-iso-propyl-3-(2'-phenylpropionyl)oxazolidin-2-one 
• 132682-23-6 (4R)-4-(hydroxymethyl)-1,3-oxazolidin-2-one 
• 177697-55-1 (4S)-4-phenyl-3-[(2R)-2-phenylpropionyl]oxazolidin-2-one 
• 1308658-87-8 C₁₇H₂₁NO₅ 
• 1308658-88-9 C₁₇H₂₁NO₅ 
• 1308658-99-2 C₂₀H₂₁NO₃ 
• 1308658-97-0 C₂₀H₂₁NO₃ 
• 1308658-79-8 C₁₇H₂₃NO₃ 
• 1308659-01-9 C₁₈H₁₆ClNO₃ 
• 1308658-92-5 C₁₅H₁₆ClNO₅ 
• 1308658-93-6 C₁₅H₁₆ClNO₅ 
• 1308658-81-2 C₁₅H₁₈ClNO₃ 

Relevant articles and documents

Visible-Light-Mediated Liberation and In Situ Conversion of Fluorophosgene

The first example for the photocatalytic generation of a highly electrophilic intermediate that is not based on radical reactivity is reported. The single-electron reduction of bench-stable and commercially available 4-(trifluoromethoxy)benzonitrile by an organic photosensitizer leads to its fragmentation into fluorophosgene and benzonitrile. The in situ generated fluorophosgene was used for the preparation of carbonates, carbamates, and urea derivatives in moderate to excellent yields via an intramolecular cyclization reaction. Transient spectroscopic investigations suggest the formation of a catalyst charge-transfer complex-dimer as the catalytic active species. Fluorophosgene as a highly reactive intermediate, was indirectly detected via its next downstream carbonyl fluoride intermediate by NMR. Furthermore, detailed NMR analyses provided a comprehensive reaction mechanism including a water dependent off-cycle equilibrium.

Carbonylation with CO2 and phosphorus electrophiles: A convenient method for the synthesis of 2-oxazolidinones from 1,2-amino alcohols

2-Oxazolidinones were prepared in good yields from 1,2-amino alcohols and CO2 in the presence of tetramethyl-phenylguanidine (PhTMG) as a base and a variety of phosphorus electrophiles under mild conditions. This procedure is advantageous over previous methodologies and relies on a novel carbonylation procedure that utilizes nontoxic CO2 and phosphorus electrophiles. Georg Thieme Verlag Stuttgart.