26575-95-1

Basic information

• Product Name: Alisol B acetate
• Synonyms: (23S,24R)-24,25-Epoxy-11b,23-dihydroxy-8a,9b,14b-dammar-13(17)-en-3-one 23-acetate;Alisol B acetate;Alisol B 23-acetate,;(8α,9β,14β,23S,24R)-11β-Hydroxy-23-acetoxy-24,25-epoxy-5α-dammara-13(17)-ene-3-one;(8α,9β,14β,23S,24R)-23-Acetoxy-24,25-epoxy-11β-hydroxydammar-13(17)-en-3-one;Acetylalisol B;ALISOL B ACETATE(SH);23-O-Acetylalisol B
• CAS NO: 26575-95-1
• Molecular Formula: C28H44O4
• Molecular Weight: 444.65
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 26575-95-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 162～163℃
• Boiling Point: 590.7 °C at 760 mmHg
• Flash Point: 179.9 °C
• Appearance: /
• Density: 1.12 g/cm³
• Refractive Index: 1.542
• Storage Temp.: 2-8°C(protect from light)
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 14.74±0.70(Predicted)
• CAS DataBase Reference: Alisol B acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Alisol B acetate(26575-95-1)
• EPA Substance Registry System: Alisol B acetate(26575-95-1)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 26575-95-1(Hazardous Substances Data)

Usage

Description

Alisol B acetate, also known as Alisol B 23-Acetate, is a herbal triterpene extract derived from various plant sources. It is a bioactive compound with potent pharmacological properties, particularly in the field of cancer treatment.

Uses

Used in Cancer Treatment:
Alisol B acetate is used as an anticancer agent, specifically for the treatment of prostate cancer. It has been found to be effective in reversing the multi-drug resistance of cancer cells that over-express P-glycoprotein, a protein that can cause resistance to chemotherapy drugs.
Used in Pharmaceutical Industry:
Alisol B acetate is used as a promising pharmaceutical candidate due to its ability to modulate various signaling pathways involved in cancer cell growth and progression. Its potential synergistic effects when combined with conventional chemotherapeutic drugs make it a valuable addition to cancer treatment strategies.
Used in Drug Delivery Systems:
Similar to gallotannin, Alisol B acetate can also benefit from novel drug delivery systems to enhance its applications and efficacy against cancer cells. The development of organic and metallic nanoparticles as carriers for Alisol B acetate delivery can improve its bioavailability and therapeutic outcomes, making it a more effective treatment option for various types of cancer.

InChI:InChI=1/C32H50O5/c1-18(16-23(36-19(2)33)27-29(5,6)37-27)20-10-14-31(8)21(20)17-22(34)26-30(7)13-12-25(35)28(3,4)24(30)11-15-32(26,31)9/h18,22-24,26-27,34H,10-17H2,1-9H3/t18-,22+,23+,24+,26+,27-,30+,31+,32+/m1/s1