267002-56-2

Basic information

• Product Name: Benzenamine, 4-chloro-2-(2-propenyl)-
• CAS NO: 267002-56-2
• Molecular Formula: C9H10ClN
• Molecular Weight: 167.638
• Mol File: 267002-56-2.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-chloro-2-(2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-chloro-2-(2-propenyl)-(267002-56-2)
• EPA Substance Registry System: Benzenamine, 4-chloro-2-(2-propenyl)-(267002-56-2)

Safety Data

• Hazardous Substances Data: 267002-56-2(Hazardous Substances Data)

Upstream product

• 1219744-20-3 C₉H₈ClNO₂ 
• 106-47-8 4-chloro-aniline 
• 18437-66-6 N-(t-butoxycarbonyl)-4-chloroaniline 
• 13519-80-7 N-allyl-4-chloroaniline 

Downstream Products

• 1255773-55-7 2-allyl-4-chloro-N-(2-methylallyl)aniline 
• 1240273-55-5 2-allyl-4-chloro-N-(2,6-dichlorobenzyl)aniline 
• 1240273-49-7 2-allyl-N-(2-chlorobenzyl)-4-chloroaniline 
• 1240273-51-1 2-allyl-4-chloro-N-(2-fluorobenzyl)aniline 
• 1215403-56-7 2-allyl-4-chloro-N-(6-chloro-2-fluorobenzyl)aniline 
• 1000848-74-7 N-(2-allyl-4-chlorophenylcarbamoyl)-p-toluenesulfonamide 
• 882787-24-8 N-(2-allyl-4-chloro-phenyl)-acrylamide 
• 839731-88-3 2-allyl-N-benzyl-4-chloroaniline 

Relevant articles and documents

Synthesis of functionalized indoles via palladium-catalyzed cyclization of N-(2-allylphenyl) benzamide: A method for synthesis of indomethacin precursor

We developed an efficient method for synthesis of substituted N-benzoylindole via Pd(II)-catalyzed C-H functionalization of substituted N-(2-allylphenyl)benzamide. The reaction showed a broad substrate scope (including N-acetyl and N-Ts substrates) and substituted indoles were obtained in good to excellent yields. The most distinctive feature of this method lies in the high selectivity for N-benzoylindole over benzoxazine, and this is the first example of Pd(II)-catalyzed synthesis of substituted N-benzoylindole. Notably, this new method was applied for the synthesis of key intermediate of indomethacin.

One-pot Construction of Difluorinated Pyrrolizidine and Indolizidine Scaffolds via Copper-Catalyzed Radical Cascade Annulation

A convenient approach to the synthesis of diverse difluorinated nitrogen-containing polycycles via a copper-catalyzed radical cascade annulation of amine-containing olefins and ethyl bromodifluoroacetate was developed. Three new bonds, including a Csp3 ?CF2 and two C?N bonds, are forged simultaneously in this strategy. Through this strategy, a series of difluorinated pyrrolizidine and indolizidine derivatives have been conveniently synthesized in good yields. (Figure presented.).

Green Organocatalytic Synthesis of Indolines and Pyrrolidines from Alkenes

Employing a green and efficient 2,2,2-trifluoroacetophenone-catalyzed oxidation of alkenes, which utilizes H2O2 as the green oxidant, a novel and sustainable synthesis of indolines and pyrrolidines was developed. This constitutes a cheap, general and environmentally-friendly protocol for the synthesis of substituted nitrogen-containing heterocycles. A variety of substitution patterns, both aromatic and aliphatic moieties, are well tolerated leading to the desired nitrogen heterocycles in good to excellent yields. (Figure presented.).