2686-86-4

Basic information

• Product Name: 3-aminopiperidine-2,6-dione hydrochloride
• Synonyms: 3-aminopiperidine-2,6-dione hydrochloride;(+-)-3-Amino-2,6-piperidinedione monohydrochloride;2,6-Piperidinedione, 3-amino-, monohydrochloride, (+-)-;Glutamic acid imide-DL-hydrochloride;3-AMinopiperidine-2,6-Dione-HCL;3-aMino-aza-cyclohexane 2,6-dione hydrochloride;3-aminopiperidine-2;6-dione hydrochloride
• CAS NO: 2686-86-4
• Molecular Formula: C5H9ClN2O2
• Molecular Weight: 164.59
• EINECS: 1592732-453-0
• Mol File: 2686-86-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 334.5 °C at 760 mmHg
• Flash Point: 156.1 °C
• Appearance: /
• Vapor Pressure: 0.000128mmHg at 25°C
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated)
• CAS DataBase Reference: 3-aminopiperidine-2,6-dione hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-aminopiperidine-2,6-dione hydrochloride(2686-86-4)
• EPA Substance Registry System: 3-aminopiperidine-2,6-dione hydrochloride(2686-86-4)

Safety Data

• Hazardous Substances Data: 2686-86-4(Hazardous Substances Data)

Usage

Uses

3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce?ubiquitination and degradation of CK1α in del(5q) MDS.?It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.

InChI:InChI=1/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H

Downstream Products

• 2361493-16-3 N-(2-(2-(2-(2-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 
• 31140-42-8 (RS)-(2,6-dioxopiperidin-3-yl)carbamic acid tert-butyl ester 
• 2098488-36-7 N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 
• 2154357-70-5 4-chloro-2-(2,6-dioxopiperidin-3-yl)-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-dione