269391-47-1

Basic information

• Product Name: BOC-2-AMINO-6-METHYLBENZOIC ACID
• Synonyms: BOC-2-AMINO-6-METHYLBENZOIC ACID
• CAS NO: 269391-47-1
• Molecular Formula: C₁₃H₁₇NO₄
• Molecular Weight: 251.28
• Mol File: 269391-47-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BOC-2-AMINO-6-METHYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-2-AMINO-6-METHYLBENZOIC ACID(269391-47-1)
• EPA Substance Registry System: BOC-2-AMINO-6-METHYLBENZOIC ACID(269391-47-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 269391-47-1(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 4389-50-8 2-amino-6-methylbenzoic acid 
• 2148-56-3 2-chloro-6-aminobenzoic acid 
• 77-92-9 citric acid 

Downstream Products

• 20877-81-0 5-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 
• 681246-37-7 3-bromo-6-[(tert-butoxycarbonyl)amino]-2-methylbenzoic acid 

Relevant articles and documents

A phosgene and peroxide-free one-pot tandem synthesis of isatoic anhydrides involving anthranilic acid, boc anhydride and 2-chloro-N-methyl pyridinium iodide

A phosgene and peroxide-free approach for the synthesis of isatoic anhydrides has been described. The synthesis involves the carbamate formation with boc anhydride followed by in situ cyclization to afford the isatoic anhydride. The importance of this synthetic strategy is in the ease of operation, scalability and preparation from readily available raw materials.

Sulfonamides having antiangiogenic and anticancer activity

Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.