270062-85-6 Usage
Description
BOC-(S)-3-AMINO-4-(4-BROMO-PHENYL)-BUTYRIC ACID is a chemical compound with the molecular formula C15H18BrNO3. It is a derivative of butyric acid, featuring a 4-bromophenyl group and an amino group protected by a tert-butyloxycarbonyl (BOC) group. BOC-(S)-3-AMINO-4-(4-BROMO-PHENYL)-BUTYRIC ACID is significant in the field of pharmaceuticals and biochemistry due to its role as a reagent in the synthesis of specific target molecules.
Uses
Used in Pharmaceutical Synthesis:
BOC-(S)-3-AMINO-4-(4-BROMO-PHENYL)-BUTYRIC ACID is used as a reagent for the synthesis of GSK 923295 (G797750), which is a potent and selective inhibitor of centromere-associated protein E. BOC-(S)-3-AMINO-4-(4-BROMO-PHENYL)-BUTYRIC ACID plays a crucial role in the development of potential therapeutic agents targeting various diseases, particularly those involving abnormal cell division or cancer.
Used in Research and Development:
In the field of research and development, BOC-(S)-3-AMINO-4-(4-BROMO-PHENYL)-BUTYRIC ACID serves as an essential building block for the creation of novel compounds with potential applications in various therapeutic areas. Its unique structure allows for the exploration of new chemical entities that may exhibit improved pharmacological properties or novel mechanisms of action.
Used in Drug Discovery:
BOC-(S)-3-AMINO-4-(4-BROMO-PHENYL)-BUTYRIC ACID is also utilized in drug discovery processes, where it can be employed to identify new lead compounds or optimize existing ones. Its structural features make it a valuable tool for medicinal chemists working on the design and synthesis of innovative therapeutic agents.
Used in Chemical Libraries:
BOC-(S)-3-AMINO-4-(4-BROMO-PHENYL)-BUTYRIC ACID can be incorporated into chemical libraries, which are collections of diverse chemical entities used for high-throughput screening in the search for new bioactive molecules. BOC-(S)-3-AMINO-4-(4-BROMO-PHENYL)-BUTYRIC ACID's inclusion in such libraries can contribute to the identification of potential drug candidates with novel pharmacological profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 270062-85-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,0,0,6 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 270062-85:
(8*2)+(7*7)+(6*0)+(5*0)+(4*6)+(3*2)+(2*8)+(1*5)=116
116 % 10 = 6
So 270062-85-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H20BrNO4/c1-15(2,3)21-14(20)17-12(9-13(18)19)8-10-4-6-11(16)7-5-10/h4-7,12H,8-9H2,1-3H3,(H,17,20)(H,18,19)/t12-/m0/s1
270062-85-6Relevant articles and documents
Synthesis of β3-homophenylalanine-derived amino acids and peptides by Suzuki coupling in solution and on solid support
Limbach, Michael,Loeweneck, Markus,Schreiber, Juerg V.,Frackenpohl, Jens,Seebach, Dieter,Billich, Andreas
, p. 1427 - 1441 (2007/10/03)
β-Peptides and, to a certain extent, also mixed α,β- peptides, are resistant to degradation by a variety of proteolytic enzymes that rapidly degrade natural α-peptides. This is one of many characteristics that make β-peptides an attractive class of compou
