270062-95-8

Basic information

• Product Name: (S)-3-AMINO-4-(4-METHYLPHENYL)BUTANOIC ACID HYDROCHLORIDE
• Synonyms: (S)-3-AMINO-4-(4-METHYLPHENYL)BUTANOIC ACID HYDROCHLORIDE;(S)-3-AMINO-4-(4-METHYL-PHENYL)-BUTYRIC ACID HCL;(S)-3-AMINO-4-(4-METHYLPHENYL)BUTYRIC ACID HYDROCHLORIDE;RARECHEM AK PT 0055;L-BETA-HOMO(4-METHYLPHENYL)ALANINE HYDROCHLORIDE;H-PHE(4-ME)-(C*CH2)OH HCL;H-BETA-HOPHE(4-ME)-OH HCL;4-METHYL-L-BETA-HOMOPHENYLALANINE HYDROCHLORIDE
• CAS NO: 270062-95-8
• Molecular Formula: C11H16ClNO2
• Molecular Weight: 229.7
• Product Categories: 3-Amino-4-phenylbutanoic Acid Analogs;B-Amino
• Mol File: 270062-95-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 345.2oC at 760 mmHg
• Flash Point: 162.6°C
• Appearance: /
• Vapor Pressure: 2.38E-05mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-3-AMINO-4-(4-METHYLPHENYL)BUTANOIC ACID HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-AMINO-4-(4-METHYLPHENYL)BUTANOIC ACID HYDROCHLORIDE(270062-95-8)
• EPA Substance Registry System: (S)-3-AMINO-4-(4-METHYLPHENYL)BUTANOIC ACID HYDROCHLORIDE(270062-95-8)

Safety Data

• Hazardous Substances Data: 270062-95-8(Hazardous Substances Data)

Usage

Uses

(S)-3-Amino-4-(4-methylphenyl)butanoic acid, HCl

InChI:InChI=1/C11H15NO2.ClH/c1-8-2-4-9(5-3-8)6-10(12)7-11(13)14;/h2-5,10H,6-7,12H2,1H3,(H,13,14);1H/t10-;/m0./s1

Upstream product

• 78861-25-3 Methyl 3-keto-4-(4'-methylphenyl)butanoate 

Relevant articles and documents

Preparation method of 3-aminopropanol or 3-aminopropionic acid derivative

The invention provides a preparation method of an optically active 3-aminopropanol or 3-aminopropionic acid derivative, and belongs to the technical field of organic synthesis. A compound having a structure as shown in a formula II and a formula III is used as a raw material, and the optically active 3-aminopropanol or 3-aminopropionic acid derivative is obtained through four basic steps, namely dehydration condensation, hydrogenation reduction, reduction and hydrolysis. The raw materials adopted in the preparation method are easy to obtain and low in cost; as a chiral phosphine-transitional metal catalyst is used in the hydrogenation reduction reaction, the optically active 3-aminopropanol or 3-aminopropionic acid derivative is efficient, high in selectivity, low in cost and suitable forlarge-scale production. Compared with existing chemical resolution and chiral introduction, the asymmetric hydrogenation synthesis method provided by the invention only produces one chiral product, ishigh in yield, and has relatively high advantages in economy and raw material utilization rate.