27151-65-1

Basic information

• Product Name: MONOMETHYL 3-METHYLGLUTARATE
• Synonyms: MONOMETHYL 3-METHYLGLUTARATE;3-METHYL-PENTANEDIOIC ACID MONOMETHYL ESTER;Monomethyl β-methylglutarate;MONOMETHYL 3-METHYLG;5-Methoxy-3-Methyl-5-oxopentanoic acid;Pentanedioic acid, 3-methyl-, 1-methyl ester
• CAS NO: 27151-65-1
• Molecular Formula: C₇H₁₂O₄
• Molecular Weight: 160.17
• Mol File: 27151-65-1.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 291.6 °C at 760 mmHg
• Flash Point: 108.4 °C
• Appearance: /
• Density: 1.123 g/cm³
• Vapor Pressure: 0.000479mmHg at 25°C
• Refractive Index: 1.442
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4?+-.0.10(Predicted)
• CAS DataBase Reference: MONOMETHYL 3-METHYLGLUTARATE(CAS DataBase Reference)
• NIST Chemistry Reference: MONOMETHYL 3-METHYLGLUTARATE(27151-65-1)
• EPA Substance Registry System: MONOMETHYL 3-METHYLGLUTARATE(27151-65-1)

Safety Data

• Hazardous Substances Data: 27151-65-1(Hazardous Substances Data)

Usage

General Description

Monomethyl 3-methylglutarate is a chemical compound that belongs to the family of carboxylic acids. It is an ester formed from the condensation of methanol and 3-methylglutaric acid. This colorless liquid is commonly used as a fragrance component in perfumes and as a flavoring agent in the food industry. It is also used in the production of various other chemicals and as a solvent in organic synthesis. Monomethyl 3-methylglutarate has a fruity, floral odor and is considered safe for use in cosmetics and personal care products. However, it should be handled with care due to its potential for skin and eye irritation.

InChI:InChI=1/C7H12O4/c1-5(3-6(8)9)4-7(10)11-2/h5H,3-4H2,1-2H3,(H,8,9)

Upstream product

• 19013-37-7 dimethyl 3-methylglutarate 
• 626-51-7 3-methyl glutaric acid 
• 67-56-1 methanol 
• 4166-53-4 3-methylglutaric anhydride 
• 124-41-4 sodium methylate 
• 63473-60-9 (S)-5-methoxy-3-methyl-5-oxopentanoic acid 

Downstream Products

• 65781-38-6 3-methylundecanoic acid 
• 1121-84-2 4-methyl-tetrahydro-pyran-2-one 
• 63473-60-9 (S)-5-methoxy-3-methyl-5-oxopentanoic acid 

Relevant articles and documents

Silica gel-supported bis-cinchona alkaloid: A chiral catalyst for the heterogeneous asymmetric desymmetrization of meso-cyclic anhydrides

A one-pot conversion of meso-cyclic anhydrides with alcoholysis in diethyl ether using SGS-(DHQ)2AQN 4, a silica gel-supported chiral catalyst, into the corresponding desymmetrized mono ester acids was achieved with enantiomeric excesses of up

Enantioselective acyl-transfer catalysis by fluoride ions

The asymmetric nucleophilic catalysis by fluoride ions at a carbon-based electrophile has been demonstrated for the first time. Using a library of ad hoc designed bifunctional phase-transfer catalysts in which both the anion and the cation are directly involved in the reaction, the desymmetrisation of meso-succinic and -glutaric anhydrides is possible.19F NMR spectroscopic studies support the intermediacy of an acyl fluoride intermediate.

Method for synthesizing muscone by utilizing beta-monomethyl methylglutarate

The invention discloses a method for synthesizing muscone by utilizing beta-monomethyl methylglutarate. According to the method, beta-monomethyl methylglutarate and alpha,omega-dodecanedioic acid monomethyl ester respectively prepared through a heteropoly acid catalytic transesterification method are used as raw materials, and Kolbe electrolysis, acyloin condensation and reduction reaction are performed to prepare the muscone. The method of the present invention has advantages of high raw material utilization rate, mold condition, easy control and environmental protection, and is suitable for industrial production .