2719-73-5Relevant articles and documents
Toward Hypoxia-Selective Rhenium and Technetium Tricarbonyl Complexes
North, Andrea J.,Hayne, David J.,Schieber, Christine,Price, Katherine,White, Anthony R.,Crouch, Peter J.,Rigopoulos, Angela,OKeefe, Graeme J.,Tochon-Danguy, Henri,Scott, Andrew M.,White, Jonathan M.,Ackermann, Uwe,Donnelly, Paul S.
, p. 9594 - 9610 (2015)
With the aim of preparing hypoxia-selective imaging and therapeutic agents, technetium(I) and rhenium(I) tricarbonyl complexes with pyridylhydrazone, dipyridylamine, and pyridylaminocarboxylate ligands containing nitrobenzyl or nitroimidazole functional g
Solvatochromic triazaborolopyridinium probes toward ultra-sensitive trace water detection in organic solvents
Chansaenpak, Kantapat,Namuangruk, Supawadee,Nootem, Jukkrit,Rashatasakhon, Paitoon,Sattayanon, Chanchai,Tumcharern, Gamolwan,Wattanathana, Worawat
, (2020/07/06)
A series of triazaborolopyridiniums (TBP) has been synthesized by varying electron-tunning substituents. The TBP derivatives with electron-withdrawing groups, including cyano, and nitro moieties, exhibited solvatochromic properties due to the internal cha
Synthesis method for 1,2,4-triazolopyridine derivative
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Paragraph 0010, (2020/06/02)
The invention provides a novel synthesis method for a 1,2,4-triazolopyridine derivative. According to the invention, the 1,2,4-triazolopyridine derivative can be obtained by taking a 2-pyridine hydrazone derivative and sodium hypochlorite as main synthesis raw materials through a reaction for 1-24 hours in an organic solvent at a temperature of 0-100 DEG C. The invention provides a synthetic method which is good in atom economy, mild in reaction conditions, simple and convenient to operate and easy to be controlled for the 1,2,4-triazolopyridine derivative.
Electrochemical synthesis of 1,2,4-triazole-fused heterocycles
Ye, Zenghui,Ding, Mingruo,Wu, Yanqi,Li, Yong,Hua, Wenkai,Zhang, Fengzhi
supporting information, p. 1732 - 1737 (2018/04/30)
A reagent-free intramolecular dehydrogenative C-N cross-coupling reaction has been developed under mild electrolytic conditions. In this atom- and step-economical one-pot process, valuable 1,2,4-triazolo[4,3-a]pyridines and related heterocyclic compounds could be synthesized efficiently from commercially available aliphatic or (hetero)aromatic aldehydes and 2-hydrazinopyridines. Various functional groups are compatible with this metal- and oxidant-free protocol which can be carried out on a gram scale easily. This novel method was applied to the synthesis of one of the top-selling drugs Xanax and late stage functionalization for generating chemical diversity in biologically relevant lead molecules.
