275356-25-7

Basic information

• Product Name: (2aR,8bR,11R)-11-phenyl-2,2a,3,4,10,11-hexahydro-9-oxa-11a-aza-pentaleno[6a,1-α]naphtalen-1-one
• Synonyms: (2aR,8bR,11R)-11-phenyl-2,2a,3,4,10,11-hexahydro-9-oxa-11a-aza-pentaleno[6a,1-α]naphtalen-1-one
• CAS NO: 275356-25-7
• Molecular Weight: 305.376
• Mol File: 275356-25-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2aR,8bR,11R)-11-phenyl-2,2a,3,4,10,11-hexahydro-9-oxa-11a-aza-pentaleno[6a,1-α]naphtalen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2aR,8bR,11R)-11-phenyl-2,2a,3,4,10,11-hexahydro-9-oxa-11a-aza-pentaleno[6a,1-α]naphtalen-1-one(275356-25-7)
• EPA Substance Registry System: (2aR,8bR,11R)-11-phenyl-2,2a,3,4,10,11-hexahydro-9-oxa-11a-aza-pentaleno[6a,1-α]naphtalen-1-one(275356-25-7)

Safety Data

• Hazardous Substances Data: 275356-25-7(Hazardous Substances Data)

Upstream product

• 6742-31-0 1,2,3,4-tetrahydro-1-oxo-2-naphthaleneacetic acid 
• 56613-80-0 D-2-phenylglycinol 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 41059-51-2 1-oxo-1,2,3,4-tetrahydro-2-naphthaleneacetic acid ethyl ester 

Downstream Products

• 275356-26-8 (3aR,9bS)-1-[(1R)-2-hydroxy-1-phenylethyl]-1,3,3a,4,5,9b-hexahydro-2H-benzo[g]indol-2-one 
• 275356-27-9 (3aR,9bS)-1-(1-Phenyl-vinyl)-1,3,3a,4,5,9b-hexahydro-benzo[g]indol-2-one 

Relevant articles and documents

Asymmetric intramolecular crossed-benzoin reactions by N-heterocyclic carbene catalysis

(Chemical Equation Presented) Getting cross: Excellent asymmetric inductions and very good yields are achieved in the generation of a quaternary stereocenter in α-hydroxy-substituted tetralones by using chiral N-heterocyclic carbene catalysts in an enantioselective intramolecular crossed-benzoin reaction. The synthesis of the corresponding α-hydroxyindanones with good ee values is also possible by this route.

Enantioselective synthesis of the pyrroloquinoline core of the martinellines

(Matrix Presented) The first enantioselective synthesis of the martinelline core (-)-3 is reported. The synthesis of (-)-3 from N-allyl-N-(benzyloxycarbonyl)-2-iodoaniline (12) proceeded in seven steps and 23% overall yield. In addition, the preparation o