27536-56-7

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Basic information

Product Name: 4ALPHA-PHORBOL 12,13-DIDECANOATE
Synonyms: 4ALPHA-PDD;4ALPHA-PHORBOL 12-13-DICAPRINATE;4ALPHA-PHORBOL 12,13-DIDECANOATE;4a-Phorbol-12,13-didecanoate;4A-PHORBOL 12,13-DIDECANOATE WEAK PROTEI N KINASE C;4α-phorbol 12-13-dicaprinate;4A-PHORBOL 12,13-DIDECANOATE, 99+%;phorbol (4alpha-) 12,13-didecanoate
CAS NO:27536-56-7
Molecular Formula: C40H64O8
Molecular Weight: 672.93
EINECS: N/A
Product Categories: metabolite
Mol File: 27536-56-7.mol
Article Data: 1

Chemical Properties

Melting Point: N/A
Boiling Point: 734.2°Cat760mmHg
Flash Point: 212.4°C
Appearance: white/solid
Density: 1.14g/cm³
Vapor Pressure: 6.92E-25mmHg at 25°C
Refractive Index: 1.546
Storage Temp.: −20°C
Solubility: DMSO: soluble
BRN: 2514324
CAS DataBase Reference: 4ALPHA-PHORBOL 12,13-DIDECANOATE(CAS DataBase Reference)
NIST Chemistry Reference: 4ALPHA-PHORBOL 12,13-DIDECANOATE(27536-56-7)
EPA Substance Registry System: 4ALPHA-PHORBOL 12,13-DIDECANOATE(27536-56-7)

Safety Data

Hazard Codes: T+
Statements: 26/27/28-40-43
Safety Statements: 36/37/39-45
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS:
F: 8-10
HazardClass: 6.1(b)
PackingGroup: III
Hazardous Substances Data: 27536-56-7(Hazardous Substances Data)

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Cas No: 27536-56-7
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4-alpha-Phorbol-12,13-didecanoate
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Dayang Chem (Hangzhou) Co.,Ltd.
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Decanoic acid,1,1'-[(1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl]ester
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Hangzhou J&H Chemical Co., Ltd.
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Acmec 4alpha-Phorbol 12,13-didecanoate solid 5mg
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Shanghai Acmec Biochemical Technology Co., Ltd.
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p-Acetotoluidide
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Henan Allgreen Chemical Co.,Ltd
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4-alpha-Phorbol 12,13-Didecanoate >99%
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4ALPHA-PHORBOL 12,13-DIDECANOATE
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ZHEJIANG JIUZHOU CHEM CO.,LTD
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Best price/ 4-alpha-Phorbol 12,13-Didecanoate >99% CAS NO.27536-56-7
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Jilin haofei import and export trade Co.,Ltd
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Decanoic acid,1,1'-[(1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl]ester
Cas No: 27536-56-7
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LC Laboratories
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27536-56-7 Usage

Uses

4α-Phorbol 12,13-didecanoate has been used as a transient receptor potential vanilloid 4 (TRPV4) agonist:to study its effects on Madin-Darby canine kidney (MDCK) cellsto study its effects on Ca2+ influx in mice fallopian tubal cellsto study its effects on hind paw swelling in mice

Biochem/physiol Actions

4α-Phorbol 12,13-didecanoate is a transient receptor potential vanilloid 4 (TRPV4) agonist. It promotes extracellular calcium influx into the cells.

Check Digit Verification of cas no

The CAS Registry Mumber 27536-56-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,5,3 and 6 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 27536-56:
(7*2)+(6*7)+(5*5)+(4*3)+(3*6)+(2*5)+(1*6)=127
127 % 10 = 7
So 27536-56-7 is a valid CAS Registry Number.

InChI:InChI=1/C40H64O8/c1-7-9-11-13-15-17-19-21-32(42)47-36-28(4)39(46)30(24-29(26-41)25-38(45)31(39)23-27(3)35(38)44)34-37(5,6)40(34,36)48-33(43)22-20-18-16-14-12-10-8-2/h23-24,28,30-31,34,36,41,45-46H,7-22,25-26H2,1-6H3/t28-,30+,31-,34-,36-,38+,39-,40-/m1/s1

27536-56-7 Well-known Company Product Price

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(Code)Product description
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Price
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Sigma
(P8014) 4α-Phorbol 12,13-didecanoate solid
27536-56-7
P8014-1MG
1,687.14CNY
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Sigma
(P8014) 4α-Phorbol 12,13-didecanoate solid
27536-56-7
P8014-5MG
6,388.20CNY
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27536-56-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name	4ALPHA-PHORBOL 12,13-DIDECANOATE

1.2 Other means of identification

Product number	-
Other names	4a-phorbol 12,13-didecanoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

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27536-56-7Relevant articles and documents

Synthesis of 4aalpha-phorbol 9-myristate 9a-acetate and related esters.

Tseng,Van Duuren,Solomon

, p. 3645 - 3649 (2007/10/14)

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