2768-55-0 Usage
General Description
Z-SER-LEU-OH DCHA is a peptide chemical compound consisting of the amino acids serine, leucine, and a C-terminal carboxylic acid group. It is commonly used in biochemical research as a model compound for studying peptide bond cleavage and enzymatic reactions due to its stable chemical properties and structural simplicity. Z-SER-LEU-OH DCHA has been shown to have potential applications in drug development, particularly in the design of peptide-based pharmaceuticals and therapeutics. Additionally, Z-SER-LEU-OH DCHA may also have utility in the development of novel biomaterials and as a tool for investigating the structure-function relationships of peptides in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 2768-55-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,6 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2768-55:
(6*2)+(5*7)+(4*6)+(3*8)+(2*5)+(1*5)=110
110 % 10 = 0
So 2768-55-0 is a valid CAS Registry Number.
2768-55-0Relevant articles and documents
Proteasome inhibitors: Synthesis and activity of arecoline oxide tripeptide derivatives
Marastoni, Mauro,McDonald, John,Baldisserotto, Anna,Canella, Alessandro,Risi, Carmela De,Pollini, Gian Piero,Tomatis, Roberto
, p. 1965 - 1968 (2007/10/03)
We describe the synthesis and biological activities of a series of methyl 3,4-epoxypiperidine-3-carboxylate tripeptide derivatives that inhibit the chymotryptic and tryptic active sites of the 20S proteasome. Of the series, compound 2 which contains 3-hydroxy-2-methylbenzoyl group at its N-terminal position, displayed the greatest inhibitory potency (IC50 1 μM). All derivatives showed favourable pharmacokinetic properties.
