28082-82-8

Basic information

• Product Name: 6,7-DIMETHYL-2(1H)-QUINOXALINONE
• Synonyms: 2-HYDROXY-6,7-DIMETHYLQUINOXALINE;6,7-DIMETHYL-2(1H)-QUINOXALINONE;6,7,-Dimethyl-2-hydroxyquinoxaline;6,7-diMethylquinoxalin-2-ol
• CAS NO: 28082-82-8
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.2
• Mol File: 28082-82-8.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 386.7 °C at 760 mmHg
• Flash Point: 187.7 °C
• Appearance: /
• Density: 1.23 g/cm³
• Vapor Pressure: 1.56E-06mmHg at 25°C
• Refractive Index: 1.626
• CAS DataBase Reference: 6,7-DIMETHYL-2(1H)-QUINOXALINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-DIMETHYL-2(1H)-QUINOXALINONE(28082-82-8)
• EPA Substance Registry System: 6,7-DIMETHYL-2(1H)-QUINOXALINONE(28082-82-8)

Safety Data

• Hazardous Substances Data: 28082-82-8(Hazardous Substances Data)

Usage

General Description

6,7-DIMETHYL-2(1H)-QUINOXALINONE is a chemical compound with the molecular formula C10H9NO. It is a derivative of quinoxaline, a heterocyclic compound containing a benzene ring fused to a pyrazine ring. 6,7-DIMETHYL-2(1H)-QUINOXALINONE is commonly used as a building block in organic synthesis and pharmaceutical research. It has been identified as a potential pharmacophore for the development of new drugs, particularly in the treatment of various diseases, including cancer, diabetes, and neurological disorders. Additionally, 6,7-DIMETHYL-2(1H)-QUINOXALINONE has also been studied for its potential use as a fluorescent dye in biochemical and biophysical applications. Overall, this chemical compound has a wide range of potential applications in both the pharmaceutical and research fields.

InChI:InChI=1/C10H10N2O/c1-6-3-8-9(4-7(6)2)12-10(13)5-11-8/h3-5H,1-2H3,(H,12,13)

Upstream product

• 922-68-9 Methyl glyoxylate 
• 3171-45-7 4,5-dimethyl-1,2-phenylenediamine 
• 924-44-7 glyoxylic acid ethyl ester 
• 105029-06-9 6,7-dimethyl-1,2,3,4-tetrahydroquinoxalin-2-one 
• 915944-24-0 methyl 4-fluoro-2-methyl-5-nitrobenzene 
• 6000-59-5 glyoxalic acid monohydrate 
• 6295-06-3 butyl glyoxalate 

Downstream Products

• 82019-34-9 1,6,7-trimethylquinoxalin-2(1Η)-one 
• 78751-23-2 6,7-Dimethyl-3-phenyl-1,2-dihydro-chinoxalin-2-on 
• 1315336-98-1 6,7-dimethyl-2-(perfluorophenyl)quinoxaline 
• 1315336-88-9 6,7-dimethylquinoxalin-2-yl 4-methylbenzenesulfonate 
• 29067-81-0 2-chloro-6,7-dimethylquinoxaline 
• 82083-10-1 6,7-Dimethyl-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-chinoxalinon 

Relevant articles and documents

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Electro-reductive C-H cyanoalkylation of quinoxalin-2(1H)-ones

Herein, we report a practical electro-reductive protocol for the direct C–H cyanoalkylation of quinoxalin-2(1H)-ones via iminyl radical-mediated ring opening. These mild reactions proceed under metal-, reductant-, and reagent-free conditions to provide synthetically useful cyanoalkylated quinoxalin-2(1H)-ones.

Electro-oxidative C-H alkylation of quinoxalin-2(1: H)-ones with organoboron compounds

Radical cleavage of C-B bonds to accomplish C-H functionalization is synthetically appealing but practically challenging. We report herein a mild electro-oxidative method for efficient C-H alkylation of quinoxalin-2(1H)-ones by means of radical addition reactions of alkyl boronic acids and esters and alkyl trifluoroborates to afford C-C coupled products. This journal is

Electrochemical chlorination and bromination of electron-deficient C[sbnd]H bonds in quinones, coumarins, quinoxalines and 1,3-diketones

The electrochemistry-promoted chlorination and bromination of electron-deficient C[sbnd]H bonds was developed, using quinones, coumarins, quinoxalines and 1,3-diketones. This protocol features readily available and safe halogen sources (hydrochloric acid and KBr), high site-selectivity and mild reaction conditions. It could provide an efficient access to a series of chlorinated and brominated quinones, coumarins, quinoxalines and 1,3-diketones.