28148-04-1Relevant articles and documents
Mohangic Acids A-E, p-Aminoacetophenonic Acids from a Marine-Mudflat-Derived Streptomyces sp.
Bae, Munhyung,Moon, Kyuho,Kim, Jihye,Park, Hyen Joo,Lee, Sang Kook,Shin, Jongheon,Oh, Dong-Chan
, p. 332 - 339 (2016)
Mohangic acids A-E (1-5) were isolated from a marine Streptomyces sp. collected from a mudflat in Buan, Republic of Korea. Comprehensive spectroscopic analysis revealed that the mohangic acids are new members of the p-aminoacetophenonic acid class. The re
FACTOR XIa INHIBITORS
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Page/Page column 53, (2017/05/21)
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma Kallikrein.
Process intensification-assisted conversion of α,ω-alkanediols to dibromides
Mekala, Shekar,Hahn, Roger C.
supporting information, p. 630 - 632 (2015/03/03)
The increasingly widespread applications of α,ω-dibromides motivated development of a scalable, inexpensive process to rapidly convert selected α,ω-alkanediols to the corresponding dibromides. Diols were heated with only 48% aq HBr and an organic solvent, using a Dean-Stark apparatus modified to fractionate the azeotropic distillate, thereby maintaining a higher HBr concentration and reaction rate in the pot. Intensified distillation also increased the reaction rate. Various other substrate, solvent, and parameter effects have been discovered and rationalized.