28383-57-5 Usage
General Description
5-bromo-1H-pyrrole-2-carboxylic acid is a chemical compound with the molecular formula C5H4BrNO2. It is a heterocyclic compound containing a pyrrole ring with a carboxylic acid group and a bromine atom attached to the pyrrole ring. 5-bromo-1H-pyrrole-2-carboxylic acid is commonly used as a building block in the synthesis of pharmaceuticals and organic compounds. It has been studied for its potential biological activities, including antimicrobial and anti-inflammatory properties. Additionally, 5-bromo-1H-pyrrole-2-carboxylic acid may also be utilized in the development of materials for various applications such as organic electronics and dye-sensitized solar cells. Overall, this chemical compound has important applications in the fields of pharmaceuticals, materials science, and organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 28383-57-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,3,8 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 28383-57:
(7*2)+(6*8)+(5*3)+(4*8)+(3*3)+(2*5)+(1*7)=135
135 % 10 = 5
So 28383-57-5 is a valid CAS Registry Number.
28383-57-5Relevant articles and documents
Synthesis of Novel Pyrazine-Substituted 1 H -Pyrrole-2-carboxamides and Related Tethered Heterocycles
Borrows, Rachel,Fairley, Gary,Feron, Lyman J. L.,Grant, Emma,Greenwood, Ryan D. R.,Howells, Rachel L.,Hughes, Samantha,Lamont, Scott G.,Lenz, Eva,McGuire, Thomas M.,Simpson, Iain
, (2022/02/10)
As part of a drug discovery program, 4-pyrazin-2-yl-1H-pyrrole-2-carboxamides were accessed along with a number of bicyclic analogues. Routes to these compounds were largely absent from the scientific literature. The synthesis of a 4-(pyrazin-2-yl)-1H-pyrrole-2-carboxamide and several fused bicyclic analogues all using standard procedures (SNAr, borylation, C C cross couplings, hydrolysis, amide bond formation, cyclisation, halogenation, and alkylation) from readily available starting materials is reported. The synthetic sequences range from 4-2 steps per final compound, with yields of isolated intermediates ranging from 20 to ?100%.
