28386-90-5

Basic information

• Product Name: 1-benzyl-5-phenyl-1H-tetrazole
• CAS NO: 28386-90-5
• Molecular Formula: C₁₄H₁₂N₄
• Molecular Weight: 236.2719
• Mol File: 28386-90-5.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 430.3°C at 760 mmHg
• Flash Point: 214°C
• Density: 1.19g/cm³
• Vapor Pressure: 1.31E-07mmHg at 25°C
• Refractive Index: 1.656
• CAS DataBase Reference: 1-benzyl-5-phenyl-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-5-phenyl-1H-tetrazole(28386-90-5)
• EPA Substance Registry System: 1-benzyl-5-phenyl-1H-tetrazole(28386-90-5)

Safety Data

• Hazardous Substances Data: 28386-90-5(Hazardous Substances Data)

Usage

General Description

1-benzyl-5-phenyl-1H-tetrazole is a chemical compound with the molecular formula C15H14N4. It is a tetrazole derivative with a benzyl group and a phenyl group attached to the tetrazole ring. 1-benzyl-5-phenyl-1H-tetrazole has been studied for its potential use as a corrosion inhibitor for metals and as a precursor for the synthesis of other organic compounds. It has also been investigated for its potential pharmacological properties, including its possible use as an antihypertensive and antithrombotic agent. Additionally, 1-benzyl-5-phenyl-1H-tetrazole has been explored for its potential use in the synthesis of polymer materials and as a component in organic light-emitting devices.

Upstream product

• 100-47-0 benzonitrile 
• 622-79-7 benzyl azide 
• 98-88-4 benzoyl chloride 
• 100-46-9 benzylamine 
• 29814-09-3 sodium salt of 5-phenyltetrazole 
• 74305-28-5 ((CH₃(CH₂)3)3P)Co(HONC(CH₃)C(CH₃)NO)2(N₄C(C₆H₅)) 
• 100-39-0 benzyl bromide 
• 161768-44-1 [1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-benzyl-amine 
• 100-44-7 benzyl chloride 
• 14309-89-8 N-benzyl-benzenecarbothioamide 
• 79344-08-4 1-benzyl-5-bromo-1H-tetrazole 
• 98-80-6 phenylboronic acid 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 5532-86-5 benzyl cyanoformate 

Downstream Products

• 1215298-35-3 methyl 2-ethoxy-1-({2′-[1-(phenylmethyl)-1H-tetrazol-5-yl][1,1′-biphenyl]-4-yl}methyl)-1H-benzimidazole-7-carboxylate 
• 1307853-85-5 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 1-({4-[2-(1-benzyl-1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-2-ethoxy-1H-1,3-benzodiazole-7-carboxylate 
• 1307853-80-0 methyl 2-(N-tert-butoxycarbonyl-N-{(2'-[1-benzyl-1H-tetrazol-5-yl]biphenyl-4-yl)methyl}amino)-3-nitrobenzoate 
• 1215298-30-8 methyl 2-[({2'-[1-benzyl-1H-tetrazol-5-yl]biphenyl-4-yl}methyl)amino]-3-nitrobenzoate 
• 1307853-81-1 methyl 2-[({2'-[1-benzyl-1H-tetrazol-5-yl]biphenyl-4-yl}methyl)amino]-3-aminobenzoate 
• 1361119-71-2 5-phenyl-2-(o-tolyl)-2H-tetrazole 
• 36215-63-1 2-(naphthalen-2-yl)-5-phenyl-2H-tetrazole 
• 1186394-26-2 N-(4-(5-phenyl-2H-tetrazol-2-yl)phenyl)acetamide 
• 18039-45-7 2,5-diphenyl-2H-tetrazole 
• 1432044-40-0 1-benzyl-5-(3',4',5'-trimethoxy-[1,1'-biphenyl]-2-yl)-1H-tetrazole 

Relevant articles and documents

Synthesis of 5-Aryl and Vinyl Tetrazoles by the Palladium-Catalyzed Cross-Coupling Reaction

A coupling reaction of 1-benzyl-5-bromotetrazole with various aryl and vinyl boronic acids via the Suzuki type reaction is found to be a general and efficient reaction for the synthesis of aryl and vinyl tetrazoles.

An Expeditious Approach to Tetrazoles from Amides Utilizing Phosphorazidates

A novel method was developed for the synthesis of tetrazoles from amides utilizing diphenyl phosphorazidate or bis(p-nitrophenyl) phosphorazidate as both the activator of amide-oxygen for elimination and azide source. Various amides were converted into th

Indium-, Magnesium-, and Zinc-Mediated Debenzylation of Protected 1 H -Tetrazoles: A Comparative Study

5-Substituted 1-benzyltetrazoles are easily debenzylated to give the corresponding deprotected tetrazoles using dissolved metals under protic conditions: Mg/MeOH, In/MeOH, or Zn/MeCO 2 H are the procedures of choice for this transformation.